Oxytocin enhances inter-brain synchrony during social coordination in male adults
Oxytocin enhances inter-brain synchrony during social coordination in male adults
复制标题
催产素增强成年男性社会协调过程中的脑间同步性
DOI：
10.1093/scan/nsw106
复制
发表时间：
2016-12-01
影响因子：
4.2
通讯作者：
Han, Shihui
中科院分区：
文献类型：
--
作者：
Mu, Yan;Guo, Chunyan;Han, Shihui
最近的脑成像研究揭示了催产素（OT）在社会交往中对个体大脑活动的影响，但很少说明OT是否以及如何调节与两个人的协调行为相关的脑间活动的一致性。我们开发了一个新的实时协调游戏，需要两个人的二分体同步与合作伙伴（协调任务）或与计算机（控制任务）在心中计数有节奏。同时记录了一对个体的脑电（EEG），以研究OT对人际协调过程中脑间神经活动同步性的影响。实验1发现，二人组显示较小的人际时间滞后的计数和更大的脑间同步的α-带神经振荡的协调（与控制）任务，这些影响是可靠的女性，但不是男性二人组观察。此外，增加的α-波段脑间同步预测所有参与者之间更好的人际行为同步。实验2，采用双盲，安慰剂对照的受试者之间的设计，揭示了鼻内OT与安慰剂管理男性二人组改善人际行为同步的协调和控制任务，但特别是增强α-波段脑间神经振荡的协调任务。我们的研究结果提供了第一个证据，OT增强了成年男性的脑间同步，以促进社会协调。
Recent brain imaging research has revealed oxytocin (OT) effects on an individual's brain activity during social interaction but tells little about whether and how OT modulates the coherence of inter-brain activity related to two individuals' coordination behavior. We developed a new real-time coordination game that required two individuals of a dyad to synchronize with a partner (coordination task) or with a computer (control task) by counting in mind rhythmically. Electroencephalography (EEG) was recorded simultaneously from a dyad to examine OT effects on inter-brain synchrony of neural activity during interpersonal coordination. Experiment 1 found that dyads showed smaller interpersonal time lags of counting and greater inter-brain synchrony of alpha-band neural oscillations during the coordination (vs control) task and these effects were reliably observed in female but not male dyads. Moreover, the increased alpha-band inter-brain synchrony predicted better interpersonal behavioral synchrony across all participants. Experiment 2, using a double blind, placebo-controlled between-subjects design, revealed that intranasal OT vs placebo administration in male dyads improved interpersonal behavioral synchrony in both the coordination and control tasks but specifically enhanced alpha-band interbrain neural oscillations during the coordination task. Our findings provide first evidence that OT enhances inter-brain synchrony in male adults to facilitate social coordination.