Influence of resistance and aerobic exercise on hunger, circulating levels of acylated ghrelin, and peptide YY in healthy males
Influence of resistance and aerobic exercise on hunger, circulating levels of acylated ghrelin, and peptide YY in healthy males
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DOI：
10.1152/ajpregu.90706.2008
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发表时间：
2009-01-01
影响因子：
2.8
通讯作者：
Stensel, David J.
中科院分区：
文献类型：
--
作者：
Broom, David R.;Batterham, Rachel L.;Stensel, David J.
Broom DR，Batterham RL，King JA，Stensel DJ.阻力和有氧运动对健康男性饥饿、循环中酰化生长素和肽YY水平的影响。Am J Physiol Regul Integr Comp Physiol 296：R29-R35，2009.首次发表于2008年11月5日; doi：10.1152/ajpregu.90706.2008。阻力（肌肉强化）运动是控制体重的运动建议的关键组成部分，但人们对阻力运动对食欲的影响知之甚少。我们研究了阻力和有氧运动对饥饿和肠激素酰化生长素和肽YY（PYY）的循环水平的影响。11名健康男性学生：年龄21.1 ± 0.3岁，体重指数23.1 ± 0.4 kg/m（2），最大摄氧量62.1 ± 1.8 ml.kg（-1）.min（-1）（平均值+/- SE），在随机交叉设计中进行了3项8小时试验，1）抗阻运动：90分钟自由举重，然后休息6.5小时，2）有氧运动：60分钟跑步，然后休息7小时，3）对照：休息8小时。每次试验2和5小时提供膳食。整个过程中测量饥饿等级和酰化生长素释放肽和PYY的血浆浓度。双因素方差分析显示饥饿、酰化生长激素释放肽和PYY的显著（P < 0.05）相互作用效应，表明在有氧运动和抗阻运动期间饥饿和酰化生长激素释放肽被抑制，而在有氧运动期间PYY增加。观察到PYY的显著试验效应，表明有氧运动试验中的浓度高于其他试验（8 h曲线下面积：对照组1，411 +/- 110，阻力1，381 +/- 97，有氧1，750 +/- 170 pg/ml 8 h）。这些研究结果表明，ghrelin和PYY可以在运动期间和运动后调节食欲，但需要进一步的研究来确定运动引起的ghrelin和PYY变化是否会影响随后的食物摄入。
Broom DR, Batterham RL, King JA, Stensel DJ. Influence of resistance and aerobic exercise on hunger, circulating levels of acylated ghrelin and peptide YY in healthy males. Am J Physiol Regul Integr Comp Physiol 296: R29-R35, 2009. First published November 5, 2008; doi:10.1152/ajpregu.90706.2008. Resistance (muscle strengthening) exercise is a key component of exercise recommendations for weight control, yet very little is known about the effects of resistance exercise on appetite. We investigated the effects of resistance and aerobic exercise on hunger and circulating levels of the gut hormones acylated ghrelin and peptide YY (PYY). Eleven healthy male students: age 21.1 +/- 0.3 yr, body mass index 23.1 +/- 0.4 kg/m(2), maximum oxygen uptake 62.1 +/- 1.8 ml.kg(-1).min(-1) (means +/- SE) undertook three, 8-h trials, 1) resistance exercise: a 90-min free weight lifting session followed by a 6.5-h rest period, 2) aerobic exercise: a 60-min run followed by a 7-h rest period, 3) control: an 8-h rest, in a randomized crossover design. Meals were provided 2 and 5 h into each trial. Hunger ratings and plasma concentrations of acylated ghrelin and PYY were measured throughout. Two-way ANOVA revealed significant (P < 0.05) interaction effects for hunger, acylated ghrelin, and PYY, indicating suppressed hunger and acylated ghrelin during aerobic and resistance exercise and increased PYY during aerobic exercise. A significant trial effect was observed for PYY, indicating higher concentrations on the aerobic exercise trial than the other trials (8 h area under the curve: control 1,411 +/- 110, resistance 1,381 +/- 97, aerobic 1,750 +/- 170 pg/ml 8 h). These findings suggest ghrelin and PYY may regulate appetite during and after exercise, but further research is required to establish whether exercise-induced changes in ghrelin and PYY influence subsequent food intake.