Histopathology after endolymphatic sac surgery for Ménière's syndrome.
Histopathology after endolymphatic sac surgery for Ménière's syndrome.
复制标题
DOI：
10.1097/mao.0b013e31821553ce
复制
发表时间：
2011-06
期刊：
影响因子：
--
通讯作者：
Merchant SN
中科院分区：
文献类型：
--
作者：
Chung JW;Fayad J;Linthicum F;Ishiyama A;Merchant SN
梅尼埃综合征囊手术的假定目标是促进内淋巴从迷路流向内淋巴囊，从而缓解积水。有很少出版的组织病理学数据是否囊手术实际上实现了这一目标。通过检查在梅尼埃综合征患者生前接受囊手术的颞骨组织病理学变化，确定囊手术是否缓解了水肿。对15例接受颞囊手术的患者进行了颞骨检查。收集有关积液的存在和严重程度、囊的组织学以及手术是否缓解眩晕的数据。5例手术未能暴露囊;其中4例眩晕缓解。囊暴露，但8例分流管未能到达囊腔; 8例中有4例眩晕缓解。在2例病例中，成功将分流管放置在囊腔内; 2例病例的眩晕均未缓解。15例均有内淋巴积水。内淋巴囊手术不能缓解梅尼埃综合征患者的积液。然而，囊手术缓解了一些患者的眩晕，但这种症状缓解的机制仍然未知。
The putative goal of sac surgery in Meniere’s syndrome is to promote the flow of endolymph from the labyrinth to the endolymphatic sac, and thereby relieving hydrops. There is scant published histopathological data whether sac surgery actually accomplishes this goal. To determine if sac surgery relieves hydrops by examining the histopathologic changes in temporal bones obtained from individuals who had undergone sac surgery during life for Meniere’s syndrome. Temporal bones were examined from 15 patients who had sac surgery. Data was collected on presence and severity of hydrops, histology of the sac, and whether the procedure relieved vertigo. The surgery failed to expose the sac in 5 cases; 4 of the 5 had relief from vertigo. The sac was exposed, but the shunt failed to reach the lumen of the sac in 8 cases; 4 of the 8 had relief from vertigo. The shunt was successfully placed within the lumen of the sac in two cases; both cases failed to experience relief from vertigo. Endolymphatic hydrops was present in all 15 cases. Endolymphatic sac surgery does not relieve hydrops in patients with Meniere’s syndrome. Yet, sac surgery relieves vertigo in some patients, but the mechanism of such symptomatic relief remains unknown.