Longitudinal trajectories of intrinsic capacity and their association with quality of life and disability
Longitudinal trajectories of intrinsic capacity and their association with quality of life and disability
复制标题
DOI：
10.1016/j.maturitas.2022.02.005
复制
发表时间：
2022-03-08
期刊：
影响因子：
4.9
通讯作者：
Manrique-Espinoza, Betty
中科院分区：
文献类型：
--
作者：
Salinas-Rodriguez, Aaron;Gonzalez-Bautista, Emmanuel;Manrique-Espinoza, Betty
目的：内在能力（IC）是世界卫生组织（WHO）健康老龄化模型中的一个关键概念。IC的系统评估可以提供一个更好的理解个人的功能轨迹。我们的目的是确定IC的纵向轨迹，并估计其与生活质量和disability.Study设计的关联：研究数据来自三波世界卫生组织研究全球老龄化和成人健康（SAGE）在墨西哥（2009年，2014年，2017年）。共纳入2735名50岁或以上的成年人。采用项目反应理论构建IC评分。我们使用生长混合模型（GMM）来研究IC的纵向轨迹。采用三水平线性混合效应模型估计IC与生活质量和残疾的相关性。主要结果测量：残疾采用WHO残疾评估表测量（WHODAS 2.0）和使用WHOQOL的生活质量结果：确定了三类：具有急剧下降轨迹的低基线IC、具有略微下降轨迹的中基线IC和具有适度增加轨迹的高基线IC。类具有更好的轨迹（较高的基线IC分数和适度增加的模式）表现出较高的生活质量分数和较低的残疾scores.Conclusions：研究结果表明，老年墨西哥成年人表现出不同的IC轨迹，这些可能与生活质量和残疾。结果突出表明，需要制定保健政策和战略，以保持内在能力和促进初级预防。
Objectives: Intrinsic capacity (IC) is a key concept within the World Health Organization's (WHO) healthy aging model. The systematic assessment of IC could provide a better understanding of the functional trajectories of individuals. Our aims were to identify the longitudinal trajectories of IC and estimate their association with quality of life and disability.Study design: The study data comes from the three waves of the WHO Study on global AGEing and adult health (SAGE) in Mexico (2009, 2014, 2017). In total, 2735 adults aged 50 years or more were included. An IC score was constructed using item response theory. We used growth mixture modeling (GMM) to investigate the longitudinal trajectories of IC. Three-level linear mixed effect models were used to estimate the associations of IC with quality of life and disability.Main outcome measures: Disability was measured using the WHO Disability Assessment Schedule (WHODAS 2.0) and quality of life using the WHOQOL (WHO Quality of Life) instrument.Results: Three classes were identified: low baseline IC with a steeply decreasing trajectory, medium baseline IC with a slightly decreasing trajectory, and high baseline IC with a moderately increasing trajectory. The class with the better trajectory (higher baseline IC score and a moderately increasing pattern) exhibited higher quality-of-life scores and lower disability scores.Conclusions: The findings show that older Mexican adults exhibit different IC trajectories, and that these may be associated with quality of life and disability. Results highlight the need for health policies and strategies to maintain intrinsic capacity and to promote primary prevention.