The association of primary hypothyroidism and inappropriate secretion of antidiuretic hormone.
The association of primary hypothyroidism and inappropriate secretion of antidiuretic hormone.
复制标题
原发性甲状腺功能减退症与抗利尿激素分泌不当的关系。
DOI：
10.1001/archinte.1965.03870060069014
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发表时间：
1965
影响因子：
--
通讯作者：
F. L. Turner
中科院分区：
文献类型：
--
作者：
A. Chinitz;F. L. Turner
近年来，抗利尿激素（ADH）2“不适当”分泌综合征是多种病因和不相关病因的各种疾病的表现。1该综合征与支气管癌、2几种脑疾病3-5（肿瘤、血管意外、头部创伤、畸形、结核性脑膜炎）、6、7急性间歇性卟啉病、8、19和结核病（粟粒性和晚期肺结核）有关。[9]迄今为止，与该综合征相关的单一内分泌障碍是甲状腺功能减退症。Goldberg和Reivich 10最近报告了一例粘液性水肿，表现为水分排泄受损和低钠血症，与ADH分泌不当一致。他们的病人甲状腺功能减退是由于服用放射性碘引起的。我们相信我们已经观察到的综合征的抗利尿激素分泌不当的患者原发性（特发性）甲状腺功能减退症。病例报告患者（编号09-65-71），一位73岁的西班牙裔美国女性，入住Bernalillo县印第安人医院
IT HAS BECOME evident in recent years that the syndrome of "inappropriate" secretion of antidiuretic hormone (ADH) 2 is a manifestation of various diseases of multiple and unrelated etiologies. 1 The syndrome has been reported in association with bronchogenic carcinoma, 2 cerebral disease of several kinds 3-5 (neoplasm, vascular accidents, head trauma, malformations, tuberculous meningitis), 6,7 acute intermittent porphyria, 8,19 and tuberculosis (miliary and advanced pulmonary). 9 The single endocrinological disturbance implicated in association with this syndrome to date has been hypothyroidism. Goldberg and Reivich 10 recently reported a case of myxedema manifesting impaired water excretion and hyponatremia consistent with inappropriate secretion of ADH. Their patient's hypothyroidism was secondary to the administration of radioactive iodine. We believe that we have observed the syndrome of inappropriate secretion of the antidiuretic hormone in a patient with primary (idiopathic) hypothyroidism. Report of a Case The patient (No. 09-65-71), a 73-year-old Spanish-American woman, was admitted to the Bernalillo County-Indian Hospital