Risk factors for hepatitis C infection among sexually transmitted disease-infected, inner city obstetric patients.
Risk factors for hepatitis C infection among sexually transmitted disease-infected, inner city obstetric patients.
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性传播的感染疾病的内部产科患者中丙型肝炎感染的危险因素。
DOI：
10.1080/10647440300025520
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发表时间：
2003
影响因子：
--
通讯作者：
McGovern, Peter G
中科院分区：
文献类型：
--
作者：
Choy, Youyin;Gittens-Williams, Lisa;Apuzzio, Joseph;Skurnick, Joan;Zollicoffer, Carl;McGovern, Peter G
目的：检验本市已感染性传播疾病(STDS)的产科患者丙型肝炎病毒感染率高于一般人群的假设，并确定特定的危险因素和高危人群。方法：对本院产前门诊(1997年7月~1999年4月)所有一种或多种性病检测阳性的患者进行丙型肝炎抗体检测。回顾了所有回来进行丙型肝炎检测的患者的病历。结果：106例性病患者进行了丙型肝炎筛查，抗丙型肝炎抗体筛查阳性率为6.6%(7/106)(95%CI=2.7~13.1%)。这一频率明显高于美国总人口中丙型肝炎的患病率(1.8%)(p=0.006)。多元Logistic回归分析证实，只有高龄(p=0.016)和艾滋病毒阳性(p=0.023)才是丙型肝炎感染的显著预测因素。结论：与一般人群相比，市中心STD感染的产科患者感染丙型肝炎的风险较高。年龄增长和艾滋病毒阳性状态是与丙型肝炎感染显著相关的危险因素。
Objective: To test the hypothesis that our inner city obstetric patients who have been infected with sexually transmitted diseases (STDs) will have a higher prevalence of hepatitis C virus infection than the general population and to identify specific risk factors and high-risk groups. Methods: All patients in our prenatal clinic (July 1997–April 1999) who tested positive for one or more STDs were asked to return for hepatitis C antibody testing. Medical charts of all patients who returned for hepatitis C testing were reviewed. Results: A total of 106 patients with STDs were tested for hepatitis C. Positive screening tests for anti-hepatitis C antibody were found in 6.6% (7/106) of the patients (95% CI = 2.7–13.1%). This frequency is significantly higher than the hepatitis C prevalence (1.8%) in the general United States population (p = 0.006). Multiple logistic regression analysis confirmed only older age (p = 0.016) and positive HIV status (p = 0.023) to be significant predictors of hepatitis C infection. Conclusions: Inner city STD-infected obstetric patients are at high risk for hepatitis C infection compared with the general population. Increasing age and HIV-positive status are risk factors which are significantly associated with hepatitis C infection.