Factor structure and familiality of first-rank symptoms in sibling pairs with schizophrenia and schizoaffective disorder
Factor structure and familiality of first-rank symptoms in sibling pairs with schizophrenia and schizoaffective disorder
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DOI：
10.1192/bjp.177.1.15
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发表时间：
2000-07-01
影响因子：
10.5
通讯作者：
Crow, TJ
中科院分区：
文献类型：
--
作者：
Loftus, J;Delisi, LE;Crow, TJ
背景 自从 Schneider 于 1937 年将其作为诊断标准引入以来，核症状在精神分裂症的概念中发挥了关键作用，但它们之间的关系以及它们与遗传易感性的关系尚不清楚。目的是确定核症状的因素结构和熟悉程度。方法核（Schneiderian）症状是从对 103 对 DSM-III-R 兄弟姐妹的研究中提取的病例记录和访谈中提取的 结果主成分分析表明有两个主要因素：一是群体认为退出、插入、广播，有控制妄想，约占方差的50%；第二，占
Background Since their introduction as diagnostic criteria by Schneider in 1937, nuclear symptoms have played a key role in concepts of schizophrenia, but their relationship to each other and to genetic predisposition has been unclear.Aims To ascertain the factor structure and familiarity of nuclear symptoms.Methods Nuclear (Schneiderian) symptoms were extracted from case notes and interviews in a study of 103 sibling pairs with DSM-III-R schizophrenia or schizoaffective disorder.Results Principal components analysis demonstrated two major factors: one, accounting for about 50% of the variance, groups thought withdrawal, insertion and broadcasting, with delusions of control; and the second, accounting for