Reliability of measured tidal volume in mechanically ventilated young pigs with normal lungs
Reliability of measured tidal volume in mechanically ventilated young pigs with normal lungs
复制标题
肺正常的机械通气仔猪潮气量测量的可靠性
作者：
M. Heulitt;Shirley J. Holt;T. Thurman;R. A. Hall;C. Jo;P. Simpson
该研究检查了是否可以在常规呼吸机的呼气阀处使用压力支持通气和呼气末正压来准确地测量容积，其中软件补偿Servo i呼吸机中可用的回路顺应性。干预在十只腹部大小和十只儿科大小的猪中测量体积，所述猪使用压力支持通气和呼气末正压，在有和没有回路顺应性补偿的情况下，用Servo i通气机通气。我们比较了呼吸速度描记法在气道开口处测得的体积在常规ventilator.Measurements和resultsThe使用电路顺应性补偿显着提高了协议的两个体积的方法在围产期大小的小猪（一致性相关系数：电路顺应性补偿，0.97，没有，0.87，p=0.002）的呼气阀测得的体积。在小儿大小的猪中，由于回路顺应性补偿，两种测量方法之间的一致性有所改善（有回路顺应性补偿的一致性相关系数为0.97;无回路顺应性补偿的一致性相关系数为0.88，p=0.027）。随着电路顺应性补偿关闭有正偏差：平均差异（偏差）2.97±0.12在apatal-sized和3.75±0.38在pediatric-sizedpigs.ConclusionsOur结果表明，可以准确地测量在新生儿和pediatric-sized动物的常规呼吸机的呼气阀的体积。
ObjectiveThis study examined whether volumes can be accurately measured at the expiratory valve of a conventional ventilator using pressure support ventilation and positive end expiratory pressure with software compensation for circuit compliance available in the Servo ί ventilator.Design and settingComparison of two methods for measuring tidal volume in an animal laboratory.SubjectsTwenty healthy, intubated, sedated, spontaneously breathing pigs.InterventionsVolume was measured in ten neonatal-sized and ten pediatric-sized pigs ventilated with the Servo ί ventilator using pressure support ventilation and positive end expiratory pressure with and without circuit compliance compensation. We compared volume measured at the airway opening by pneumotachography to volume measured at the expiratory valve of a conventional ventilator.Measurements and resultsThe use of circuit compliance compensation significantly improved the agreement between the two volume methods in neonatal-sized piglets (concordance correlation coefficient: with circuit compliance compensation, 0.97; without, 0.87, p=0.002). In pediatric-sized pigs there was improvement in agreement between the two measurement methods due to circuit compliance compensation (concordance correlation coefficient with circuit compliance compensation, 0.97; without, 0.88, p=0.027). With circuit compliance compensation off there was positive bias: mean difference (bias) 2.97±0.12 in neonatal-sized and 3.75±0.38 in pediatric-sized pigs.ConclusionsOur results show that volume can be accurately measured at the expiratory valve of a conventional ventilator in neonatal- and pediatric-sized animals.