Urinary tract infection: Self reported incidence and associated costs
Urinary tract infection: Self reported incidence and associated costs
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DOI：
10.1016/s1047-2797(00)00072-7
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发表时间：
2000-11-01
影响因子：
5.6
通讯作者：
Sobel, JD
中科院分区：
文献类型：
--
作者：
Foxman, B;Barlow, R;Sobel, JD
目的：按年龄估算推定尿路感染 (UTI) 的年发病率、累积概率以及社会成本。方法：对美国 2000 名女性进行的随机数字拨号调查进行分析。结果：10.8%（95% CI：9.4，12.1%）的 18 岁及以上女性报告在过去 12 个月内至少发生过一次推定尿路感染，其中大多数病例发生在一生中有两次或两次以上尿路感染史的女性。我们估计，到 24 岁时，三分之一的女性将至少患有一种经医生诊断的尿路感染，并接受处方药治疗。总体而言，估计 1995 年美国有 1130 万女性至少有一次推定的尿路感染接受了抗生素治疗。我们估计 1995 年，通过处方治疗尿路感染病例的年度费用为 16 亿美元。如果 1995 年之后发生的费用每年折算 5%，则 20 年内的总费用现值为 255 亿美元。结论：如果开发出一种疫苗，可以预防初始或复发性尿路感染给社会带来的净效益将是巨大的，即使要付出 10 亿美元的发展成本。 (C) 2000 Elsevier Science Inc. 保留所有权利。
PURPOSE: To estimate the annual incidence, cumulative probability of presumed urinary tract infection (UTI) by age, and the social costs.METHODS: Analysis of a random digit dialing survey of 2000 women in the United States.RESULTS: 10.8 percent (95% CI: 9.4, 12.1%) of women aged 18 and older reported at least one presumed UTI during the past 12 months, with the majority of the cases occurring among women with a history of two or more UTI episodes in their life. We estimate that by age 24, one third of women will have at least one physician-diagnosed UTI that was treated with prescription medication. Overall, an estimated 11.3 million women in the United States had at least one presumed UTI treated with antibiotics in 1995. We estimate the annual cost of UTI cases with prescriptions to be $1.6 billion in 1995. If the costs occurring after 1995 are discounted at 5% annually, the total cost over 20 years has a present value of $25.5 billion.CONCLUSION: If a vaccine were developed that would prevent either initial or recurrent UTI the net benefits to society would be substantial, even at a developmental cost of one billion dollars. (C) 2000 Elsevier Science Inc. All rights reserved.