Henoch-Schönlein purpura nephritis associated with polycythemia vera.
Henoch-Schönlein purpura nephritis associated with polycythemia vera.
复制标题
过敏性紫癜肾炎与真性红细胞增多症相关。
作者：
M. Kanauchi;K. Dohi;H. Shiiki;Yoshihiro Fuiii;H. Ishikawa
我们报告一位53岁的男性，在真性红细胞增多症治疗过程中出现快速进展的肾小球肾炎和Henoch-Schönlein紫癜。初步肾活检标本显示系膜增生性肾小球肾炎。患者因皮肤紫癜和进行性肾衰竭入院，接受了700毫克雷莫司汀治疗真性红细胞增多症29个月。第二个肾活检标本显示新月形肾小球肾炎伴免疫荧光IgA沉积。这些数据表明Henoch-Schönlein紫癜性肾炎可能是对瑞莫司汀治疗的反应。
We present a 53-year-old man with rapidly progressive glomerulonephritis and Henoch-Schönlein purpura which developed during the course of treatment for polycythemia vera. An initial renal biopsy specimen showed mesangial proliferative glomerulonephritis. The patient was admitted to the hospital with cutaneous purpura and progressive renal failure after having received 700 mg of ranimustine over a 29 month period as therapy for the polycythemia vera. A second renal biopsy specimen revealed crescentic glomerulonephritis with deposition of immunofluorescent IgA. These data suggest that Henoch-Schönlein purpura nephritis may occur in response to ranimustine therapy.