Emerging diseases. New coronavirus reveals some of its secrets.
Emerging diseases. New coronavirus reveals some of its secrets.
复制标题
新出现的疾病。
DOI：
10.1126/science.340.6128.17
复制
发表时间：
2013
期刊：
影响因子：
56.9
通讯作者：
M. Enserink
中科院分区：
文献类型：
--
作者：
M. Enserink
在首次报道SARS样病毒的六个月后，科学家们确信感染的人数比已知的17例还要多，但他们不知道有多少人;他们假设病毒起源于动物，但他们不知道是哪个物种。几乎可以肯定的是，病毒会在人与人之间传播，但目前还不清楚这种传播的效率有多高，也不清楚它是否有可能爆发成一场全球性的健康危机。自该病毒出现以来，科学家们已经公布了从患者身上分离出的四种菌株的基因组，开发了诊断测试，并着手开发动物模型。但考虑到阿拉伯半岛的流行病学存在许多问题，一些研究人员希望在不同时间和地点发现的病毒基因组可能会为正在发生的事情提供线索。
Six months after a SARS-like virus was first reported, scientists are convinced that there are more people infected than the 17 known cases, but they don9t know how many; they assume the virus originates in animals, but they don9t know in which species. There is almost certainly human-to-human transmission, but it9s unclear how efficiently it occurs or if it has the potential to explode into a global health crisis. Since the virus emerged, scientists have published genomes of four strains isolated from patients, developed diagnostic tests, and set out to develop animal models. But given the many questions about the epidemiology in the Arabian Peninsula, some researchers are hoping that the genomes of viruses found at different times and locales may yield clues about what is happening.