Determinants of allergen concentrations in apartments of asthmatic children living in public housing
Determinants of allergen concentrations in apartments of asthmatic children living in public housing
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DOI：
10.1007/s11524-006-9146-2
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发表时间：
2007-03-01
影响因子：
6.6
通讯作者：
Spengler, John D.
中科院分区：
文献类型：
--
作者：
Peters, Junenette L.;Levy, Jonathan I.;Spengler, John D.
越来越多的证据表明，糟糕的住房条件与包括哮喘在内的呼吸道疾病有关。市中心的住房条件和哮喘之间的联系在一定程度上被归因于蟑螂和老鼠的侵扰以及由此导致的过敏原暴露。多种社会和行为因素会影响环境暴露和健康状况，因此有必要对这些因素进行彻底检查。作为健康公共住房倡议的一部分，我们在马萨诸塞州波士顿的三个公共住房开发项目中评估了身体特征和家庭特征与虫害相关过敏原水平之间的关联。我们在卧室空气、床上检测到蟑螂过敏原(Bla g 1和B la g 2)，特别是厨房样本中的高浓度。在控制发育和季节的多变量Tobit回归中，公寓的杂乱和缺乏清洁与空气中Bla g 1浓度增加10倍，床上Bla g 1浓度增加7倍，床上Bla g 2浓度增加8倍，厨房Bla g 2浓度增加11倍相关(p<；0.05)。墙上/天花板上的洞与厨房蟑螂过敏原浓度增加6至11倍有关(p
There is growing evidence linking poor housing conditions and respiratory diseases, including asthma. The association between housing conditions and asthma in the inner city has been attributed in part to cockroach and mouse infestation and the resulting allergen exposures. Multiple social and behavioral factors can influence environmental exposures and health conditions, necessitating a thorough examination of such factors. As part of the Healthy Public Housing Initiative, we evaluated the association between physical and household characteristics and pest-related allergen levels in three public housing developments in Boston, MA. We detected cockroach allergens (Bla g 1 and Bla g 2) in bedroom air, bed, and especially high concentrations in kitchen samples. In multivariate Tobit regressions controlling for development and season, clutter and lack of cleanliness in the apartment were associated with a tenfold increase in Bla g 1 concentration in the air, a sevenfold increase in Bla g 1 and an eightfold increase in Bla g 2 concentrations in the bed, and an 11-fold increase in Bla g 2 in the kitchen (p < 0.05 for all). Holes in the wall/ceiling were associated with a six- to 11-fold increase in kitchen cockroach allergen concentrations (p