DISTRIBUTION OF GABAERGIC NEURONS AND TERMINALS IN THE AUDITORY-SYSTEM OF THE BARN OWL
DISTRIBUTION OF GABAERGIC NEURONS AND TERMINALS IN THE AUDITORY-SYSTEM OF THE BARN OWL
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DOI：
10.1002/cne.902860205
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发表时间：
1989-08-08
影响因子：
2.5
通讯作者：
KONISHI, M
中科院分区：
文献类型：
--
作者：
CARR, CE;FUJITA, I;KONISHI, M
用谷氨酸脱羧酶（GAD）和γ-氨基丁酸（GABA）抗血清，观察了仓鸮脑干和中脑听核团中GABA能细胞的分布。猫头鹰在不同的通路中处理听觉信号的时间和强度分量，并且每条通路具有独特的GAD和GABA样免疫反应性模式。在时间通路中，耳蜗大细胞核和板状核的所有细胞都接受体周GABA能终末，少量GABA能神经元包围着这两个核。外侧丘系腹侧核（前区）含有免疫反应终末和一些GABA能神经元。在强度通路中，密集的免疫反应终末分布在耳蜗角核，其中也含有少量的GABA能神经元。上级橄榄含有两种GABA能细胞类型的免疫反应终末，分布于整个神经元。外侧丘系核（腹侧部分）的所有神经元似乎都是GABA能的，并且该核还含有中等数量的免疫反应终末。免疫反应终末分布于外侧丘系腹侧核（后分裂）的整个神经元，而多极和小梭形GABA能神经元在核的背侧区域占主导地位。时间和强度通路在下丘结合联合收割机。下丘中央核含有大量的梭形和星状GABA能神经元和密集的免疫反应终末丛，而外核含有少量的免疫反应细胞和终末。浅核内有密集、细小的免疫反应终末和少量GABA能神经元。
Antisera to GAD (glutamic acid decarboxylase) and GABA were used to determine the distribution of GABAergic cells in the brainstem and midbrain auditory nuclei of the barn owl. The owl processes time and intensity components of the auditory signal in the separate pathways, and each pathway has a distinctive pattern of GAD- and GABA-like immunoreactivity. In the time pathway, all the cells of the cochlear nucleus magnocellularis and nucleus laminaris receive perisomatic GABAergic terminals, and small numbers of GABAergic neurons surround both nuclei. The ventral nucleus of the lateral lemniscus (anterior division) contains both immunoreactive terminals and some GABAergic neurons. In the intensity pathway, dense immunoreactive terminals are distributed throughout the cochlear nucleus angularis, which also contains a small number of GABAergic neurons. The superior olive contains two GABAergic cell types of immunoreactive terminals distributed thoughout the neuropil. All the neurons of the nucleus of the lateral lemniscus (ventral part) appear to be GABAergic and this nucleus also contains a moderate number of immunoreactive terminals. Immunoreactive terminals are distributed throughout the neuropil of the ventral nucleus of the lateral lemniscus (posterior division), whereas multipolar and small fusiform GABAergic neurons predominate in the dorsal regions of the nucleus. The time and intensity pathways combine in the inferior colliculus. The central nucleus of the inferior colliculus contains a large number of fusiform and stellate GABAergic neurons and a dense plexus of immunoreactive terminals, whereas the external nucleus contains slightly fewer immunoreactive cells and terminals. The superficial nucleus contains dense, fine immunoreactive terminals and a small number of GABAergic neurons.