MODIFICATION OF AN OUTBREAK OF INFLUENZA IN TECUMSEH, MICHIGAN BY VACCINATION OF SCHOOLCHILDREN

MODIFICATION OF AN OUTBREAK OF INFLUENZA IN TECUMSEH, MICHIGAN BY VACCINATION OF SCHOOLCHILDREN
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DOI:
10.1093/infdis/122.1-2.16
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发表时间:
1970-01-01
影响因子:
6.4
通讯作者:
FRANCIS, T
FRANCIS, T
中科院分区:
医学2区
文献类型:
--
作者:
MONTO, AS;DAVENPORT, FM;FRANCIS, T

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方法社区。特库姆塞是一座位于密歇根州东南部、拥有 7,500 人口的城市。该城市和周边半农村地区的总人口为 10,000,自 1959 年以来一直在对慢性疾病进行纵向调查,自 1965 年以来一直在对急性感染进行研究 [6]。为了监测呼吸道疾病,经过培训的非专业访谈员每周都会联系一组家庭,以确定是否出现任何新疾病。如果在发病后 2 天内报告疾病,则收集微生物分离样本。在初次报告后的几周内,将提出具体的后续问题以确定病程。这些家庭被监视一年,然后由其他人代替。 1968-1969年秋冬季,从社区所有有儿童的家庭中随机抽取60%的家庭,成年成员年龄在45岁以下。其余为1名成员患有慢性呼吸系统或心血管疾病的家庭;还包括匹配的比较或对照家庭。
MethodsThe communities. Tecumseh is a city with a population of 7,500 located in southeastern Michigan. The city and surrounding semirural area, with a total population of 10,000, has been under study since 1959 in a longitudinal investigation of chronic diseases and, since 1965, of acute infections [6]. For the surveillance of respiratory diseases, a panel of families is contacted weekly by trained lay interviewers to determine if there have been any new illnesses. Specimens for microbial isolation are collected if the illness is reported within 2 days of onset. In the weeks following the initial report, specificfollow-up questions are asked to determine the course of the illness. The families are kept under surveillance for 1 year and are then replaced by others. During the fall and winter of 1968-1969, 60% of the families were drawn randomly from all families in the community with children, whose adult members were under 45. The remainder were families in which 1 member had a chronic respiratory or cardiovascular disease; also included were matched comparison or control families.