Very low-grade albuminuria reflects susceptibility to chronic kidney disease in combination with cardiovascular risk factors

Very low-grade albuminuria reflects susceptibility to chronic kidney disease in combination with cardiovascular risk factors
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DOI:
10.1038/hr.2010.39
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发表时间:
2010-06-01
影响因子:
5.4
通讯作者:
Kim, Suhnggwon
Kim, Suhnggwon
中科院分区:
医学2区
文献类型:
--
作者:
Heo, Nam Ju;Ahn, Jeong Myung;Kim, Suhnggwon

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低度白蛋白尿被认为是一种心血管危险因素,低于微量白蛋白尿的常规截止点,微量白蛋白尿以前被认为是心血管疾病和慢性肾脏疾病(CKD)的标志物。代谢综合征也被证明与微量白蛋白尿和CKD有关。我们评估了5998名非糖尿病受试者中低度白蛋白尿、CKD和代谢综合征之间的关系。受试者分为6组:尿白蛋白/肌酐比值(UACR)
Low-grade albuminuria has been proposed as a cardiovascular risk factor that is below the conventional cut-off point for microalbuminuria, which has been previously identified as a marker for cardiovascular disease and chronic kidney disease (CKD). Metabolic syndrome has also been shown to be related with microalbuminuria and CKD. We assessed the relationship among low-grade albuminuria, CKD and metabolic syndrome among 5998 non-diabetic subjects. The subjects were divided into six groups: subjects with urine albumin-to-creatinine ratio (UACR)