Copper(I) Chloride-Catalyzed Aerobic Oxidative Arylation of Glycine Ester and Amide Derivatives
Copper(I) Chloride-Catalyzed Aerobic Oxidative Arylation of Glycine Ester and Amide Derivatives
复制标题
氯化铜(I)催化甘氨酸酯和酰胺衍生物的有氧氧化芳基化
DOI：
10.1002/adsc.201300535
复制
发表时间：
2014-02-10
影响因子：
5.4
通讯作者：
Yuan, Yong
中科院分区：
文献类型：
--
作者：
Huo, Congde;Wang, Cheng;Yuan, Yong
已经开发出一种简单高效的氯化铜（I）催化的甘氨酸衍生物（甘氨酸酯、甘氨酸酰胺和短肽）与吲哚的有氧氧化偶联。该反应在不存在任何其他添加剂的温和条件下进行，仅需要简单的铜盐作为催化剂和氧气作为助氧化剂。
A simple and efficient copper(I) chloride- catalyzed aerobic oxidative coupling of glycine de- rivatives (glycine esters, glycine amides and short peptides) with indoles has been developed. The re- action is performed in the absence of any other ad- ditives under mild conditions and only requires simple copper salts as a catalyst and oxygen as a co- oxidant.