Effect of bolus volume and flow time on temporospatial coordination in oropharyngeal pressure production in healthy subjects
Effect of bolus volume and flow time on temporospatial coordination in oropharyngeal pressure production in healthy subjects
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DOI：
10.1016/j.physbeh.2018.03.006
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发表时间：
2018-05
影响因子：
2.9
通讯作者：
J. Yano;Y. Aoyagi;T. Ono;K. Hori;W. Yamaguchi;Shigehiro Fujiwara;I. Kumakura
中科院分区：
文献类型：
--
作者：
J. Yano;Y. Aoyagi;T. Ono;K. Hori;W. Yamaguchi;Shigehiro Fujiwara;I. Kumakura
推注量和流动时间对舌压（TP）和咽压（PP）的顺序协调的影响尚不清楚，这在吞咽的生物力学中是重要的。在这项研究中，我们测量TP和PP同时在10个健康成年人在多个点在干吞咽和吞咽5毫升和15毫升的液体具有不同的粘度，并调查的时间的变化的开始，峰值和偏移这些压力。使用硬腭上具有5个测量点的传感器片系统测量TP，使用具有4个测量点的测压导管测量PP。在同步波形上分析了各测压点压力产生的起始、峰值和偏移时间等顺序事件的顺序和相关性。我们发现，TP和PP的起效时间之间的差异减少时，团注量较大。大剂量体积的变化对峰值时间或偏移时间的影响很小。推注的流动时间影响TP和PP的起效和达峰时间。随着流动时间的增加，TP和PP之间出现时间差，TP开始出现在PP之前。这可能是第一个详细的压力-流量动力学分析，将口腔和咽视为一个单一的功能单元。我们相信，我们的分析是扩展未来研究的重要一步，包括更广泛的年龄组和吞咽困难患者。
The effects of bolus volume and flow time on the sequential coordination of tongue pressure (TP) and pharyngeal pressure (PP), which are important in the biomechanics of swallowing, are unclear. In this study, we measured TP and PP simultaneously in 10 healthy adults at multiple points during dry swallowing and the swallowing of 5 ml and 15 ml of liquids with different viscosities, and investigated changes in the timing of the onset, peak, and offset of these pressures. TP was measured using a sensor sheet system with five measuring points on the hard palate, and PP was measured using a manometry catheter with four measuring points. The order and correlations of sequential events, such as onset, peak, and offset times of pressure production, at each pressure measuring point were analyzed on the synchronized waveforms. We found that the differences between the TP and PP onset times decreased when the bolus volume was larger. The change in bolus volume had very little effect on peak time or offset time. The flow time of the bolus affected the appearance of onset and peak time for both TP and PP. A time difference between TP and PP emerged as the flow time increased, with TP starting to appear before PP. This may be the first detailed analysis of pressure-flow dynamics that treats the mouth and pharynx as a single functional unit. We believe that our analysis is an important step toward extending future research to include a wider range of age groups and dysphagia patients.