Mental disorder in adults with intellectual disability. I: Prevalence of functional psychiatric illness among a community-based population aged between 16 and 64 years

Mental disorder in adults with intellectual disability. I: Prevalence of functional psychiatric illness among a community-based population aged between 16 and 64 years
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DOI:
10.1046/j.1365-2788.2001.00374.x
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发表时间:
2001-12-01
影响因子:
3.6
通讯作者:
Bright, C
Bright, C
中科院分区:
医学3区
文献类型:
--
作者:
Deb, S;Thomas, M;Bright, C

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据报道,智力残疾(ID)成人中精神疾病的患病率在10%至39%之间变化很大;然而,存在许多方法上的问题。本研究的目的是建立功能性精神疾病的患病率与ID谁住在社区的成年人之间,以比较整体率和类型的精神疾病的人口与ID和一般人口没有ID之间,并建立与精神疾病的危险因素与ID的成年人。在第一部分中,一名训练有素的精神科医生采访了101名随机选择的ID成年人及其照顾者,使用成人发育障碍简易精神病评估表(Mini PAS-ADD)筛选精神病病例。在这101名成年人中,go具有足够的沟通能力,使Mini PAS-ADD的管理成为可能。第二个受过训练的精神病学家采访了20名成年人中的IG,他们根据最初的迷你PAS-ADD访谈被诊断为精神病病例。这位精神病学家采访了病人和他们的照顾者在秋季PAS-ADD采访。第二位精神科医生对根据迷你PAS-ADD问卷做出的初步诊断一无所知。根据国际疾病分类-第10次修订版(ICD-10)标准进行最终精神病诊断。约14.4%(95%置信区间= 7.4-21.4%)的队列患者根据ICD-10标准进行了精神病诊断:4.4%患有精神分裂症,2.2%患有抑郁症,2.2%患有广泛性焦虑症,4.4%患有恐怖症,1%患有妄想症。功能性精神疾病的总体患病率(点患病率)与一般人群(16%)相似。然而,精神分裂症和恐怖症的发病率在研究队列中显著高于一般人群(分别为0.4%和1.1%)。年龄增长和身体残疾的存在与精神疾病的发生显著相关,根据严重残疾人诊断评估(DASH)问卷,在剩余的11名严重ID成人中,有2名(18%)被诊断为精神疾病(1名躁狂症和1名焦虑症)。
The reported prevalence of psychiatric illness among adults with intellectual disability (ID) varies widely between 10 and 39%; however, many methodological problems exist. The aims of the present study were to establish the prevalence of functional psychiatric illness among adults with ID who live in the community, in order to compare the overall rate and types of psychiatric illness between the population with ID and the general population without ID, and to establish the risk factors associated with psychiatric illness in adults with ID. The study was done in two stages. In the first part, a trained psychiatrist interviewed 101 randomly selected adults with ID and their carers using the Mini Psychiatric Assessment Schedule for adults with Developmental Disability (Mini PAS-ADD) to screen for psychiatric caseness. Out of these 101 adults, go had sufficient communicative abilities that made the administration of Mini PAS-ADD possible. A second trained psychiatrist interviewed ig out of the 20 adults who were diagnosed as psychiatric cases according to the initial Mini PAS-ADD interview. This psychiatrist interviewed patients and their carers in line with the fall PAS-ADD interview. The second psychiatrist was blind to the initial diagnoses made according to the Mini PAS-ADD questionnaire. A final psychiatric diagnosis was made according to International Classification of Diseases - 10th Revision (ICD-10) criteria. Some 14.4% (95% confidence interval = 7.4-21.4%) of the cohort had a psychiatric diagnosis according to ICD-10 criteria: 4.4% had schizophrenia, 2.2% depressive disorder, 2.2% generalized anxiety disorder, 4.4% phobic disorder and 1% delusional disorder. The overall rate of functional psychiatric illness (point prevalence) was similar to that found in the general population (16%). However, the rates of schizophrenic illness and phobic disorder were significantly higher in the study cohort compared with those in the general population (0.4% and 1.1%, respectively). Increasing age and the presence of physical disability were significantly associated with the occurrence of psychiatric illness, Out of the 11 remaining adults with severe ID, two (18%) had a diagnosis of a psychiatric illness (one mania and one anxiety disorder) according to the Diagnostic Assessment for the Severely Handicapped (DASH) questionnaire.