IntAct: an open source molecular interaction database

IntAct: an open source molecular interaction database
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DOI:
10.1093/nar/gkh052
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发表时间:
2004-01-01
影响因子:
14.9
通讯作者:
Apweller, R
Apweller, R
中科院分区:
生物学2区
文献类型:
--
作者:
Hermjakob, H;Montecchi-Palazzi, L;Apweller, R

文献摘要

被引文献

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IntAct提供了一个开源的数据库和工具包,用于存储、呈现和分析蛋白质相互作用。网络界面提供了蛋白质相互作用的文本和图形表示,并允许在相互作用蛋白质的GO注释的背景下探索相互作用网络。Web服务允许直接计算访问以XML格式检索交互网络。IntAct目前包含从文献中导入的类似2200个二进制和复杂的相互作用,并与Swiss-Prot团队合作策划,密集使用受控词汇表以确保数据一致性。所有IntAct软件、数据和受控词汇均可在http://www.ebi.ac.uk/intact上获得。
IntAct provides an open source database and toolkit for the storage, presentation and analysis of protein interactions. The web interface provides both textual and graphical representations of protein interactions, and allows exploring interaction networks in the context of the GO annotations of the interacting proteins. A web service allows direct computational access to retrieve interaction networks in XML format. IntAct currently contains similar to 2200 binary and complex interactions imported from the literature and curated in collaboration with the Swiss-Prot team, making intensive use of controlled vocabularies to ensure data consistency. All IntAct software, data and controlled vocabularies are available at http://www.ebi.ac.uk/intact.