Relations between continuous performance test performance measures and ADHD behaviors
Relations between continuous performance test performance measures and ADHD behaviors
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DOI：
10.1023/a:1025405216339
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发表时间：
2003-10-01
影响因子：
3.6
通讯作者：
Angold, A
中科院分区：
文献类型：
--
作者：
Epstein, JN;Erkanli, A;Angold, A
Conners’s Continuous Performance Test （CPT）是一项神经心理学测试，已经多次被证明可以将ADHD与正常人群区分开来。Conners的CPT可以衍生出几个变量，包括遗漏和委托误差，平均命中反应时间（RT），平均命中RT标准误差，d'和beta。每个CPT参数实际评估的内容在很大程度上是基于临床假设和每个测量的表面效度（例如，遗漏错误测量注意力不集中，委托错误测量冲动）。本研究试图检验各种CPT变量与表型行为之间的关系，从而更好地理解各种CPT变量。对817名儿童的流行病学样本进行了Conners的CPT。与父母进行诊断访谈，以确定所有儿童的ADHD症状概况。诊断为ADHD的儿童有更多的可变RTs，犯更多的委托和遗漏错误，并且表现出比未诊断的儿童更差的感知敏感性。对于具体症状，采用广义估计方程（GEE）和ANCOVAs来确定18种DSM-IV ADHD症状与6项CPT参数之间的具体关系。CPT表现测量显示与ADHD症状有显著关系，但根据先验假设没有显示症状域特异性。两种信号检测指标d'和β的总体表现与所有ADHD症状高度相关。此外，随着时间的推移，RTs的变异性增加与大多数ADHD症状有关。最后，似乎至少有一个CPT变量，即平均hit RT，与ADHD症状总体上的关系最小，但在与多动症状的联系中确实显示出一些特异性。
The Conners' Continuous Performance Test (CPT) is a neuropsychological task that has repeatedly been shown to differentiate ADHD from normal groups. Several variables may be derived from the Conners' CPT including errors of omission and commission, mean hit reaction time(RT), mean hit RT standard error, d', and beta. What each CPT parameter actually assesses has largely been based upon clinical assumptions and the face validity of each measure (e.g., omission errors measure inattention, commission errors measure impulsivity). This study attempts to examine relations between various CPT variables and phenotypic behaviors so as to better understand the various CPT variables. An epidemiological sample of 817 children was administered the Conners' CPT. Diagnostic interviews were conducted with parents to determine ADHD symptom profiles for all children. Children diagnosed with ADHD had more variable RTs, made more errors of commission and omission, and demonstrated poorer perceptual sensitivity than nondiagnosed children. Regarding specific symptoms, generalized estimating equations (GEE) and ANCOVAs were conducted to determine specific relationships between the 18 DSM-IV ADHD symptoms and 6 CPT parameters. CPT performance measures demonstrated significant relationships to ADHD symptoms but did not demonstrate symptom domain specificity according to a priori assumptions. Overall performance on the two signal detection measures, d' and beta, was highly related to all ADHD symptoms across symptom domains. Further, increased variability in RTs over time was related to most ADHD symptoms. Finally, it appears that at least 1 CPT variable, mean hit RT, is minimally related to ADHD symptoms as a whole, but does demonstrate some specificity in its link with symptoms of hyperactivity.