Inhibitors of HCVNS5B polymerase:: Synthesis and structure-activity relationships of N-alkyl-4-hydroxyquinolon-3-yl-benzothiadiazine sulfamides
Inhibitors of HCVNS5B polymerase:: Synthesis and structure-activity relationships of N-alkyl-4-hydroxyquinolon-3-yl-benzothiadiazine sulfamides
复制标题
DOI：
10.1016/j.bmcl.2006.04.015
复制
发表时间：
2006-07-01
影响因子：
2.7
通讯作者：
Kempf, Dale J.
中科院分区：
文献类型：
--
作者：
Krueger, A. Chris;Madigan, Darold L.;Kempf, Dale J.
研究了取代的N-烷基-4-羟基喹啉-3-基-苯并噻二嗪磺酰胺作为基因型I HCV聚合酶的抑制剂。这类化合物的构效关系模式进行了讨论。(c)2006爱思唯尔有限公司保留所有权利。
Substituted N-alkyl-4-hydroxyquinolon-3-yl-benzothiadiazine sulfamides were investigated as inhibitors of genotype I HCV polymerase. Structure-activity relationship patterns for this class of compounds are discussed. (c) 2006 Elsevier Ltd. All rights reserved.