Continuous-slice PENN-PET: a positron tomograph with volume imaging capability.
Continuous-slice PENN-PET: a positron tomograph with volume imaging capability.
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发表时间：
1990-05
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通讯作者：
Joel S. Karp;G. Muehllehner;D. Mankoff;Caesar E. Ordonez;John M. Ollinger;M. Daube-Witherspoon;Arthur T. Haigh;D. Beerbohm
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作者：
Joel S. Karp;G. Muehllehner;D. Mankoff;Caesar E. Ordonez;John M. Ollinger;M. Daube-Witherspoon;Arthur T. Haigh;D. Beerbohm
PENN-PET扫描仪由六个六边形排列的位置敏感Nal（TI）探测器组成。这种设计在所有三个维度上提供高空间分辨率、沿所有三个轴沿着的高采样密度而无需扫描器运动、大的轴向接受角、良好的能量分辨率和良好的定时分辨率。这导致具有高灵敏度和低散射及随机背景的三维成像能力。在中心附近的所有方向上的空间分辨率为5.5 mm（FWHM）。对于大脑大小的物体，真实灵敏度最大为85 kcps/microCi/ml，散射分数最小为10%，两者都取决于较低水平的能量阈值。扫描仪可以在视场中处理高达5 mCi的数据，此时随机数等于真正的符合，探测器达到其计数率极限。到目前为止，我们已经获得了[18F]FDG脑部研究和心脏研究，这表明我们的扫描仪适用于脑部和全身成像。根据迄今为止的结果，我们认为这种设计产生了一种简单而高性能的扫描仪，适用于许多类型的静态和动态临床研究。
The PENN-PET scanner consists of six hexagonally arranged position-sensitive Nal(TI) detectors. This design offers high spatial resolution in all three dimensions, high sampling density along all three axes without scanner motion, a large axial acceptance angle, good energy resolution, and good timing resolution. This results in three-dimensional imaging capability with high sensitivity and low scatter and random backgrounds. The spatial resolution is 5.5 mm (FWHM) in all directions near the center. The true sensitivity, for a brain-sized object, is a maximum of 85 kcps/microCi/ml and the scatter fraction is a minimum of 10%, both depending on the lower level energy threshold. The scanner can handle up to 5 mCi in the field of view, at which point the randoms equal the true coincidences and the detectors reach their count rate limit. We have so far acquired [18F]FDG brain studies and cardiac studies, which show the applicability of our scanner for both brain and whole-body imaging. With the results to date, we feel that this design results in a simple yet high performance scanner which is applicable to many types of static and dynamic clinical studies.