Risk factors for fatal childhood diarrhea: a case-control study from two remote Panamanian islands.
Risk factors for fatal childhood diarrhea: a case-control study from two remote Panamanian islands.
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致命性儿童腹泻的危险因素：来自巴拿马两个偏远岛屿的病例对照研究。
DOI：
10.1093/oxfordjournals.aje.a114039
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发表时间：
1985
影响因子：
5
通讯作者：
Sack,RB
中科院分区：
文献类型：
--
作者：
Ryder,RW;Reeves,WC;Sack,RB
在1979年9月至1980年3月期间，在对生活在巴拿马加勒比海沿岸圣比亚斯群岛的库纳印第安儿童进行的病例对照调查中，寻找由相同病原体引起的致命性和非致命性腹泻病例之间的区别特征。8例致命性腹泻病例（4例与轮状病毒相关，1例与蓝氏贾第鞭毛虫相关，3例无可识别病原体）发生在186名年龄小于5岁的儿童队列中，随访7个月，与同期发生的24例非致命性腹泻病例相匹配。身高体重测量值低于参考标准的第90百分位数，依赖传统药物而不是同等的西药，以及未能接受口服补液溶液在致命性病例中比非致命性病例更常见。将传统医学人员长期以来在整个村庄的权威纳入扩大的社区健康教育计划，强调口服补液溶液早期治疗腹泻的重要性，可能会降低该人群中与腹泻疾病相关的死亡率。
Between September 1979 and March 1980, distinguishing features between fatal and nonfatal cases of diarrhea caused by the same etiologic agents were sought in a case-control investigation of Cuna Indian children living on the San Bias Islands located off Panama's Caribbean coast. The eight fatal cases of diarrhea (four associated with rotavirus, one withGiardia lambiia, and three without identifiable pathogens), which occurred in a cohort of 186 children aged less than five years who were followed for seven months, were matched with 24 contemporaneously occurring nonfatal cases of diarrhea. Weight-for-length measurements falling below the 90th percentile of the reference standard, reliance on traditional rather than equally as available Western medicine, and failure to receive oral rehydration solution were significantly more common among fatal than nonfatal cases. Incorporating traditional medicine men with their long-standing village-wide authority into expanded community health education programs that emphasize the importance of early treatment of diarrhea with oral rehydration solution would probably reduce mortality associated with diarrheal illness in this population.