INCIDENCE OF ACETYLCHOLINE RECEPTOR-ANTIBODY-POSITIVE MYASTHENIA GRAVIS IN SOUTH AFRICA
INCIDENCE OF ACETYLCHOLINE RECEPTOR-ANTIBODY-POSITIVE MYASTHENIA GRAVIS IN SOUTH AFRICA
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DOI:
10.1002/mus.24348
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发表时间:
2015-04-01
期刊:
影响因子:
3.4
通讯作者:
Heckmann, Jeannine M.
中科院分区:
文献类型:
--
作者:
Mombaur, Busisiwe;Lesosky, Maia R.;Heckmann, Jeannine M.
IntroductionThe aim of this study was to assess age- and gender-specific incidence rates (IRs) of acetylcholine receptor (AChR)-antibody-positive myasthenia gravis (MG) in South Africa, and geographical variations in incidence.MethodsIRs were calculated from positive AChR-antibody laboratory data between 2011 and 2012, using 2011 population census data.Results890 individuals were seropositive, for an annual IR of 8.5 per million. Age-standardized IR for early-onset (