Predominant Leptospira spp. serovars in serological diagnosis of canines and humans in the City of Uberlândia, State of Minas Gerais, Brazil
Predominant Leptospira spp. serovars in serological diagnosis of canines and humans in the City of Uberlândia, State of Minas Gerais, Brazil
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DOI：
10.1590/s0037-86822011005000012
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发表时间：
2011-04-01
影响因子：
2
通讯作者：
Lima-Ribeiro, Anna Monteiro Correia
中科院分区：
文献类型：
--
作者：
Castro, Jacqueline Ribeiro de;Salaberry, Sandra Renata Sampaio;Lima-Ribeiro, Anna Monteiro Correia
引言：本研究旨在验证主要钩端螺旋体属的发生情况。2008年通报的家犬和人类血清型，以及巴西米纳斯吉拉斯州乌贝兰迪亚市对该疾病的地理方法中的主要风险因素。研究方法：2008年8月，在动物狂犬病疫苗接种活动期间，采集了来自乌贝兰迪亚北方、南方、东部、西部和中央卫生区不同地区的犬血清样本（n=268）。2008年期间，对该市进行了地理评估，包括对周边地区、废物填埋场、垃圾收集、啮齿动物通报、人类钩端螺旋体病病例和溢流区的位置进行评估。钩端螺旋体病的诊断使用显微镜凝集试验（MAT），动物和人类钩端螺旋体病诊断的金标准。结果如下：犬主要对Autumnalis（34.2%）和Tarassovi（23.7%）血清型反应，而在人类中，登记病例中Tarassovi血清型占优势。这些血清型的发生可能与两个物种共有的感染源有关，或者犬可能是人类的感染源。东部卫生区显示有更多的反应性狗。结论：2008年乌贝兰迪亚市的狗和人发生了钩端螺旋体病。这种经常被忽视的疾病必须加以预防，因为它是一种公共卫生风险，与登革热等其他地方病相似。
Introduction: This study aimed to verify the occurrence of the principal Leptospira spp. serovars in domestic dogs and humans, notified in 2008, and the main risk factors in a geographic approach to the disease in the city of Uberlandia, State of Minas Gerais, Brazil. Methods: Canine blood serum samples (n=268) from different districts, belonging to the Northern, Southern, Eastern, Western and Central Sanitary Districts of Uberlandia, were collected during an animal vaccination campaign against rabies, in August 2008. A geographic approach to the city was conducted, including evaluation of locations in peripheral areas, waste landfills, garbage collection, rodent notification, human leptospirosis cases and overflow flood areas, during 2008. Leptospirosis was diagnosed using the microscopic agglutination test (MAT), the gold standard for animal and human leptospirosis diagnosis. Results: Dogs mainly reacted to Autumnalis (34.2%) and Tarassovi (23.7%) serovars, while in humans, predominance of Tarassovi serovars occurred in the cases registered. The occurrence of these serovars could be related to an infection source common to both species, or dogs could be the infection source for humans. The Eastern Sanitary District showed a greater number of reactive dogs. Conclusions: Leptospirosis occurred in dogs and humans of the city of Uberlandia in 2008. This often neglected disease must be prevented because represents a public health risk and resembles other endemic illness like dengue.