Marine natural products.
Marine natural products.
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DOI：
10.1039/a804469d
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发表时间：
2000
影响因子：
11.9
通讯作者：
D. J. Faulkner
中科院分区：
文献类型：
--
作者：
D. J. Faulkner
本报告是对1999年海洋天然产物文献的回顾。本期刊早先发表的报告涵盖1977年至1998年12月期间的情况。与1998年相比，去年相对平静，尽管据报道在大多数方面都取得了稳步进展。再一次，海绵是天然产品研究中最受欢迎的生物，被囊动物和腔肠动物紧随其后。海洋生物技术的加速进展在海洋天然产物化学上留下了印记，其形式是强调海洋微生物和与海洋微生物的共生关系的论文稳步增加。关于海洋天然产物生物合成的研究，也带有最新基因技术的标记，在本杂志的其他地方进行了综述。海洋天然产物仍然是合成的主要目标，尽管报告部分和正式合成的论文数量远远超过记录全部合成的更有用的论文，特别是重新定义海洋天然产物结构的合成研究。这份报告继续强调了生物活性
This report is a review of the marine natural products literature for 1999. Earlier reports published in this journal cover the period from 1977 to December 1998. In comparison with 1998, the last year was relatively quiet although steady progress was reported on most fronts. Once again, sponges were the favourite organisms for natural product studies, with tunicates and coelenterates following close behind. The accelerating advances in marine biotechnology have made their mark on marine natural products chemistry in the form of a steady increase in papers emphasizing marine microorganisms and symbiotic relationships involving marine microbes. Studies of the biosynthesis of marine natural products, which also bear the mark of the latest genetic techniques, are reviewed elsewhere in this journal. Marine natural products continue to be prime targets for synthesis although papers reporting partial and formal syntheses, which are not included in this review, far outnumber the more useful papers that record total syntheses and, in particular, synthetic studies that redefine the structures of marine natural products. This report continues to emphasize the bioactivity