A novel and efficient method for inside selective esterification of terminal vic-diols
A novel and efficient method for inside selective esterification of terminal vic-diols
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DOI：
10.1016/j.tetlet.2003.11.128
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发表时间：
2004-02-02
影响因子：
1.8
通讯作者：
Imanishi, T
中科院分区：
文献类型：
--
作者：
Ikejiri, M;Miyashita, K;Imanishi, T
通过Yb（OTf）（3）催化环原酸酯的形成和部分水解，实现了一种新型高效的末端邻二醇内选择性酯化反应。该方法提供了几个优点，包括与酸不稳定官能团的广泛相容性，以及良好到高的区域选择性和产率。(C)2003爱思唯尔有限公司。保留所有权利。
A novel and highly efficient procedure for inside selective esterification of terminal vic-diols has been achieved in one-pot via Yb(OTf)(3)-catalyzed formation and partial hydrolysis of cyclic orthoesters. This method offers several advantages including wide compatibility with acid labile functional groups, and good to high regioselectivity and yields. (C) 2003 Elsevier Ltd. All rights reserved.