A cancer cell specific targeting nanocomplex for combination of mRNA-responsive photodynamic and chemo-therapy
A cancer cell specific targeting nanocomplex for combination of mRNA-responsive photodynamic and chemo-therapy
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用于结合 mRNA 响应光动力和化疗的癌细胞特异性靶向纳米复合物
DOI：
10.1039/c7cc05295b
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发表时间：
2017
影响因子：
4.9
通讯作者：
Liu Jingfeng
中科院分区：
文献类型：
--
作者：
Zhang Xiaolong;Tan Xionghong;Zhang Da;Liao Naishun;Zheng Youshi;Zheng Aixian;Zeng Yongyi;Liu Xiaolong;Liu Jingfeng
我们开发了一种癌症细胞特异性靶向纳米复合物，通过精确响应细胞内肿瘤相关mRNA，将光动力治疗与化疗相结合。两种方法联合治疗对癌细胞的治疗效果明显增强。
We have developed a cancer cell specific targeting nanocomplex which combines photodynamic therapy with chemotherapy through precisely responding to the intracellular tumor-related mRNA. The combined treatment of these two modalities showed significantly enhanced therapeutic effects on cancer cells.