Ratio of inhibited-to-activated pallidal neurons decreases dramatically during passive limb movement in the MPTP-treated monkey

Ratio of inhibited-to-activated pallidal neurons decreases dramatically during passive limb movement in the MPTP-treated monkey
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DOI:
10.1152/jn.2000.83.3.1760
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发表时间:
2000-03-01
影响因子:
2.5
通讯作者:
Gross, CE
Gross, CE
中科院分区:
医学3区
文献类型:
--
作者:
Boraud, T;Bezard, E;Gross, CE

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Mink在1996年提出了一个假设,即基底神经节(BG)的作用主要是集中选择;鼓励运动机制诱导期望的运动和抑制竞争机制。这意味着,在正常受试者中,与运动相关的苍白球内侧部(GPi)神经元的抑制与激活(I/A)比率
Mink advanced the hypothesis in 1996 that the role of the basal ganglia (BG) is primarily one of focused selection; the encouragement of motor mechanisms inducing a desired movement and the inhibition of competing mechanisms. This would imply, in normal subjects, a ratio of inhibited-to-activated (I/A) movement-related globus pallidus pars internalis (GPi) neurons