Syntheses of Sulfilimines by Iron-Catalyzed Iminations of Sulfides with 2,2,2-Trichloroethyl Sulfamate
Syntheses of Sulfilimines by Iron-Catalyzed Iminations of Sulfides with 2,2,2-Trichloroethyl Sulfamate
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DOI：
10.1021/acs.joc.4c01250
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发表时间：
2024-06-13
影响因子：
3.6
通讯作者：
Bolm，Carsten
中科院分区：
文献类型：
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作者：
Periasamy，Kiruthika;Gordeeva，Sofya;Bolm，Carsten
以2,2,2-三氯乙基氨基磺酸盐（H2NTces）、（二乙酰氧基碘）苯（PIDA）和催化量的三酸铁为原料，对硫化物进行模拟反应，制备了n保护的亚胺类化合物。该反应在室温下进行，仅在3小时后就可以得到具有各种官能团和（杂）芳基取代基的大量无环和环ntc -亚胺。通过随后的氧化和脱保护，产物转化为intonh -亚砜胺。
N-protected sulfilimines are prepared by imination of sulfides with a combination of 2,2,2-trichloroethyl sulfamate (H2NTces), (diacetoxyiodo)benzene (PIDA), and a catalytic amount of iron triflate. The reaction proceeds at room temperature, and after only 3 h a wide range of acyclic and cyclicNTces-sulfilimines with various functional groups and (hetero)aryl substituents can be obtained. By subsequent oxidation followed by deprotection, the products are converted intoNH-sulfoximines.