COMPUTER CONTROL OF A MODIFIED LANGENDORFF PERFUSION APPARATUS FOR ORGAN PRESERVATION USING CRYOPROTECTIVE AGENTS
COMPUTER CONTROL OF A MODIFIED LANGENDORFF PERFUSION APPARATUS FOR ORGAN PRESERVATION USING CRYOPROTECTIVE AGENTS
复制标题
DOI：
10.1016/0141-5425(81)90006-6
复制
发表时间：
1981-01-01
期刊：
影响因子：
--
通讯作者：
HARNESS, JB
中科院分区：
文献类型：
--
作者：
ADEM, CG;HARNESS, JB
本文介绍了一种与过程控制计算机相连的离体大鼠心脏低温保存装置的结构。该设备的灵活性是通过在多个和可变条件下同时进行两组实验来证明的。计算机控制程序允许仪器的交互式校准，精确控制变量和修改实验过程中的参数。通过控制灌注液蠕动泵的速度，灌注压不允许超过当前水平。报道了允许在-22 ℃下储存大鼠心脏[用于移植]的实验。在低温保护剂乙二醇的帮助下。
The construction of an isolated rat heart cryopreservation apparatus which is interfaced to a process-control computer is described. The flexibility of the equipment is demonstrated by the running of simultaneous dual sets of experiments under multiple and variable conditions. The computer-control program allows interactive calibration of the instruments, accurate control of variables and modification of parameters during the experiments. By controlling the speed of the perfusate''s peristaltic pump, perfusion pressure was not allowed to exceed a present level. Experiments are reported which allow the storage of rat hearts [for transplantation] at -22.degree. C with the aid of the cryoprotective agent, ethylene glycol.