Amiodarone-induced hyperthyroidism in a patient with functioning papillary carcinoma of the thyroid and extensive hepatic metastases.
Amiodarone-induced hyperthyroidism in a patient with functioning papillary carcinoma of the thyroid and extensive hepatic metastases.
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DOI：
10.1089/thy.2005.15.1337
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发表时间：
2005-12
期刊：
影响因子：
--
通讯作者：
G. Mackie;B. Shulkin
中科院分区：
文献类型：
--
作者：
G. Mackie;B. Shulkin
产生甲状腺激素的甲状腺癌是一种罕见的甲状腺毒症病因。我们报告了一例高分化癌广泛肝转移的病例。胺碘酮治疗心房颤动导致甲亢的发展。甲状腺癌患者由含碘化合物引起的甲状腺毒症沉淀是罕见的。相对较高的碘负荷和缓慢的胺碘酮消除使这类患者的临床管理复杂化。
Thyroid hormone producing thyroid carcinoma is an uncommon cause of thyrotoxicosis. A patient with extensive hepatic metastases from well-differentiated carcinoma is presented. Administration of amiodarone for atrial fibrillation led to the development of hyperthyroidism. Precipitation of thyrotoxicosis by iodine-containing compounds in patients with thyroid carcinoma is rare. The relatively high iodine load and the slow elimination of amiodarone complicate the clinical management of such patients.