Self-appraisal decisions evoke dissociated dorsal-ventral aMPFC networks
Self-appraisal decisions evoke dissociated dorsal-ventral aMPFC networks
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DOI：
10.1016/j.neuroimage.2005.10.030
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发表时间：
2006-04-15
期刊：
影响因子：
5.7
通讯作者：
Johnson, SC
中科院分区：
文献类型：
--
作者：
Schmitz, TW;Johnson, SC
前内侧前额叶皮质(AMPFC)在个人显著的决策过程中持续活跃，但不同的贡献者)，该区域在背腹轴上的过程却鲜为人知。使用自我评估决策任务和功能磁共振成像，我们展示了腹侧aMPFC与杏仁核、岛核和伏隔核的任务依赖性连接，以及背侧aMPFC与背侧PFC和双侧海马的连接。这些aMPFC网络似乎辅助了自我评价决策所固有的不同的贡献过程，特别是背侧中介的认知网络和腹侧中介的情感/自我相关网络。(C)2005 Elsevier Inc.保留所有权利。
The anterior medial prefrontal cortex (aMPFC) is consistently active during personally salient decisions, yet the differential contributor), processes of this region along the dorsal-ventral axis are less understood. Using a self-appraisal decision-making task and functional magnetic resonance imaging, we demonstrated task-dependent connectivity of ventral aMPFC with amygdala, insula, and nucleus accumbens, and dorsal aMPFC connectivity with dorsolateral PFC and bilateral hippocampus. These aMPFC networks appear to subserve distinct contributory processes inherent to self-appraisal decisions, specifically a dorsally mediated cognitive and a ventrally mediated affective/self-relevance network. (c) 2005 Elsevier Inc. All rights reserved.