Bioavailability of calcium from calcium carbonate, DL-calcium lactate, L-calcium lactate and powdered oyster shell calcium in vitamin D-deficient or -replete rats.
Bioavailability of calcium from calcium carbonate, DL-calcium lactate, L-calcium lactate and powdered oyster shell calcium in vitamin D-deficient or -replete rats.
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DOI：
10.1248/bpb.18.677
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发表时间：
1995-05
影响因子：
2
通讯作者：
N. Tsugawa;T. Okano;R. Higashino;T. Kimura;Y. Oshio;Y. Teraoka;C. Igarashi;I. Ezawa;T. Kobayashi
中科院分区：
文献类型：
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作者：
N. Tsugawa;T. Okano;R. Higashino;T. Kimura;Y. Oshio;Y. Teraoka;C. Igarashi;I. Ezawa;T. Kobayashi
来自各种钙源的钙在人类和动物中的生物利用度已经是研究多年的主题，并且关于不同钙盐的相对生物利用度存在相当大的争议。大多数研究使用钙平衡技术，在性能和解释方面存在许多问题。使用一种用于评估钙盐中钙用于血浆钙代谢和骨矿化的功效的方法，我们检查了来自四种市售钙盐的钙的生物利用度，即碳酸钙、DL-乳酸钙、L-乳酸钙和粉末状牡蛎壳钙在维生素D缺乏或充足的大鼠中。通过两组大鼠的方差分析测试，在钙盐中，生物利用度的差异很小，并且没有统计学意义。因此，我们得出结论，钙是利用到相同的程度，从碳酸钙，DL-乳酸钙，L-乳酸钙和粉末牡蛎壳钙在维生素D缺乏和-充满大鼠。
The bioavailability of calcium from various calcium sources in humans and animals has been the subject of investigation for many years and there is considerable controversy as to the relative bioavailability of different calcium salts. Most of the studies have used a calcium balance technique which has numerous problems in terms of performance and interpretation. Using a method for evaluating the efficacy of calcium from calcium salts used for plasma calcium metabolism and bone mineralization, we examined the bioavailability of calcium from four commercially available calcium salts, namely calcium carbonate, DL-calcium lactate, L-calcium lactate and powdered oyster shell-calcium in vitamin D-deficient or -replete rats. Among the calcium salts, the differences in bioavailability were small and not statistically significant as tested by analysis of variance in both groups of rats. Thus, we conclude that calcium is utilized to the same extent from calcium carbonate, DL-calcium lactate, L-calcium lactate and powered oyster shell-calcium in both vitamin D-deficient and -replete rats.