Lung function in older humans: the contribution of body composition, physical activity and smoking
Lung function in older humans: the contribution of body composition, physical activity and smoking
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DOI：
10.1080/03014460010029758
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发表时间：
2001-09-01
影响因子：
1.7
通讯作者：
Cunningham, DA
中科院分区：
文献类型：
--
作者：
Amara, CE;Koval, JJ;Cunningham, DA
使用异速生长模型来确定与55-86岁独立生活的男性和女性的用力呼气量(FEV1.0)下降相关的重要因素。测量数据来自居住在加拿大安大略省伦敦市的181名男性和203名女性的随机样本。使用异速生长模型评估身高、年龄、性别、肥胖、无脂肪质量(FFM)、握力和体力活动(PA)对FEV1.0的影响，以检验肺功能的性别差异将部分归因于上述变量的性别差异，因此我们的分析将消除这一假设。将以下模型线性化，并用标准多元回归确定参数：FEV1.0=身高(Beta1)。FFMbeta2.握力(Beta3)。PA(Beta4)。实验(β0+β5年龄+β6性+β7吸烟+β8%体脂)。是一个元素。结果表明，老年人参与的FFM量和大强度体力活动对用力呼气功能的影响可能比先前所认为的更重要。此外，这项研究的结果证实了年龄和身高在预测FEV1.0中的重要性，并证明了吸烟对肺功能的负面影响。FFM和体力活动水平较高的个体往往与高于平均水平的肺功能表现相关。根据我们的模型确定的FEV1.0的横截面下降率约为每十年12%。
An allometric model was used to determine the important factors related to the decline in forced expiratory volume (FEV1.0) across ages 55-86 years in independently living men and women. Measurements were available from a randomized sample of 181 men and 203 women residing in London, Ontario, Canada. The effects of height, age, sex, adiposity, fat free mass (FFM), grip strength and physical activity (PA) on FEV1.0 were assessed using an allometric model to test the hypothesis that sex differences in lung function would be due in part to sex-related differences in the aforementioned variables and would therefore be eliminated by our analysis. The following model was linearized and parameters were identified using standard multiple regression: FEV1.0 = height(beta1) . FFMbeta2 . grip strength(beta3) . PA(beta4) . exp (beta0 + beta 5age + beta 6sex + beta 7smoking + beta8% body fat) . is an element of. Results indicate that the amount of FFM and heavy intensity physical activity participated in by the elderly may be more important in influencing forced expiratory function than previously recognized. In addition, results from this study have confirmed the importance of age and height in the prediction of FEV1.0 and demonstrated a negative effect of smoking on lung function. Individuals with a greater FFM and physical activity level tended to be associated with an above average lung function performance. The cross-sectional rate of decline in FEV1.0 determined from our model was approximate to 12% per decade.