Adult T-cell Lymphoma Complicated with Epidermodysplasia Verruciformis-like Eruptions.

Adult T-cell Lymphoma Complicated with Epidermodysplasia Verruciformis-like Eruptions.
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DOI:
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发表时间:
2015-12
期刊:
Acta dermatovenerologica Croatica : ADC
影响因子:
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通讯作者:
N. Nakai;Akifumi Ohshita;J. Kuroda;N. Katoh
N. Nakai;Akifumi Ohshita;J. Kuroda;N. Katoh
中科院分区:
其他
文献类型:
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作者:
N. Nakai;Akifumi Ohshita;J. Kuroda;N. Katoh

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成人T细胞淋巴瘤(ATL)最早由Uchiyama等人报道。(1)作为一种明显的成熟T细胞恶性肿瘤,主要发生在出生于日本西南部的患者中(2)。儿童时期患有疣状表皮发育不良(EV)的患者有许多细小、粉红色、扁平的丘疹和斑块,类似于扁平疣(3)。EV主要由人乳头瘤病毒(HPV)5型和8型引起,但也由HPV9型、12型、14型、15型、17型、19型、25型、36型、38型、47型和50型(3)引起。最近,在免疫抑制的患者中观察到了EV样皮疹,特别是那些患有人类免疫缺陷病毒(HIV)(3例)、默克尔细胞癌(MCC)(4-6例)和肾移植(7,8例)的患者。在此,我们报告一例罕见的ATL皮疹合并EV样皮疹。
Adult T-cell lymphoma (ATL) was first reported by Uchiyama et al. (1) as a distinct malignancy of mature T cells occurring primarily in patients born in southwestern Japan (2). Patients with epidermodysplasia verruciformis (EV) present in childhood with numerous thin, pink, flat papules and plaques that resemble verruca plana (3). EV is mainly caused by the human papilloma virus (HPV) types 5 and 8, but also by HPV types 9, 12, 14, 15, 17, 19, 25, 36, 38, 47, and 50 (3). Recently, EV-like eruptions have been observed in immunosuppressed patients, especially those with human immunodeficiency virus (HIV) (3), Merkel cell carcinoma (MCC) (4-6), and renal transplantation (7,8). Herein, we report a rare case of skin eruptions of ATL complicated with EV-like eruptions.