Photoacoustic needle: minimally invasive guidance to biopsy
Photoacoustic needle: minimally invasive guidance to biopsy
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DOI：
10.1117/1.jbo.18.7.070502
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发表时间：
2013-07-01
影响因子：
3.5
通讯作者：
Manohar, Srirang
中科院分区：
文献类型：
--
作者：
Piras, Daniele;Grijsen, Chiel;Manohar, Srirang
我们引入了一种基于光声（PA）的针探头，以扩展光学针方法在引导活检中的范围。脉冲光耦合到要插入组织中的针中的光纤，并且使用用于针引导的超声成像仪来检测PA信号。该PA针采样量大，并具有成像组件，以便对光纤的轴前和轴外位置进行测量。这允许在后续步骤中导航这些区域以进行光学表征和直接活检。这个概念是探讨简单的幻影和生物标本。(c)作者。由SPIE根据知识共享归因3.0未移植许可证发布。分发或复制本作品的全部或部分需要原始出版物的全部归属，包括其DOI。
We introduce a needle probe based on photoacoustics (PA) to extend the scope of optical needle methods in guiding biopsies. Pulsed light is coupled to an optical fiber in a needle to be inserted in tissue, and PA signals are detected using an ultrasound imager used for needle guidance. This PA needle samples large volumes and possesses an imaging component so that sites forward and off-axis of the fiber are surveyed. This allows navigation of those regions for optical characterization and direct biopsy in a subsequent step. The concept is explored on simple phantoms and biological specimens. (c) The Authors. Published by SPIE under a Creative Commons Attribution 3.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.