Premotor neurons in the feeding system of Aplysia californica.
Premotor neurons in the feeding system of Aplysia californica.
复制标题
海兔进食系统中的运动前神经元。
DOI：
10.1002/neu.480200516
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发表时间：
1989
期刊：
影响因子：
--
通讯作者：
Kirk,MD
中科院分区：
文献类型：
--
作者：
Kirk,MD
中央模式发生器 (CPG) 电路控制节律行为的循环电机输出。尽管对海兔食物引起的摄食唤起和饱足感进行了广泛的行为和细胞研究，但人们对控制有节奏的完成摄食行为的神经元回路知之甚少。然而，最近的研究发现，海兔的吞咽和排泄过程中，运动前神经元能够启动和维持颊运动程序。其他新发现的神经元接收来自 CPG 的突触输入，进而与颊运动神经元进行突触并控制其输出。其中一些神经元及其在颊系统内的作用受到内源性神经肽的调节。有了这些信息，我们就可以开始了解神经元网络如何控制颊运动输出，以及如何调节它们的活动以产生观察到的进食行为的灵活性。
Central pattern generator (CPG) circuits control cyclic motor output underlying rhythmic behaviors. Although there have been extensive behavioral and cellular studies of food‐induced feeding arousal as well as satiation inAplysia, very little is known about the neuronal circuits controlling rhythmic consummatory feeding behavior. However, recent studies have identified premotor neurons that initiate and maintain buccal motor programs underlying ingesion and egestion inAplysia. Other newly identified neurons receive synaptic input from feeding CPGs and in turn synapse with and control the output of buccal motor neurons. Some of these neurons and their effects within the buccal system are modulated by endogenous neuropeptides. With this information we can begin to understand how neuronal networks control buccal motor output and how their activity is modulated to produce flexibility in observed feeding behavior.