Tooth Discoloration after Regenerative Endodontic Procedures with Calcium Silicate-Based Cements-An Ex Vivo Study
Tooth Discoloration after Regenerative Endodontic Procedures with Calcium Silicate-Based Cements-An Ex Vivo Study
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DOI：
10.3390/app10175793
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发表时间：
2020-09-01
影响因子：
2.7
通讯作者：
Santos, Joao Miguel
中科院分区：
文献类型：
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作者：
Palma, Paulo J.;Marques, Joana A.;Santos, Joao Miguel
本离体研究的目的是评估和比较四种用于再生牙髓手术（REP）的牙髓生物材料引起的冠变色。在所有54颗牙齿中，在牙骨质与釉质交界处顶端2 mm处水平进行牙根切除。进入髓室后，将样本随机分组，并填充生理盐水或血液，然后放置硅酸钙基骨水泥（CSC）：ProRoot矿物三氧化物聚合物（MTA）（Dentsply Sirona），Biodentine（Septodont），TotalFill BC（FKG）或盖髓材料（PCM）（Coltene）。使用L* a* B* 系统在5个不同时间点（生物材料应用前和应用后即刻、72小时、7天和6个月）评估颜色变化（Δ E）。统计分析的显著性水平设定为p < 0.05。Δ E随时间的变化存在统计学显著差异（p< 0.001）。考虑到材料（p< 0.001）、处理（p= 0.007）或两者（p= 0.002），发现了统计学差异。如果仅考虑材料或处理，则无论时间如何，均检测到统计学显著性差异（p< 0.001）。经过六个月的评估，血液暴露可能是生物材料颜色变化的关键因素。Biodentine的变色可能性最低，其次是TotalFill和PCM，尽管没有统计学显著差异。MTA表现出最大的颜色变化。生物材料的选择应考虑材料的变色潜力。
The aim of the present ex vivo study was to assess and compare coronal discoloration induced by four endodontic biomaterials used in regenerative endodontic procedures (REPs). Root resection was executed horizontally, 2 mm apical to the cementoenamel junction, in all fifty-four teeth. After accessing the pulp chamber, specimens were randomly divided in groups and filled with either saline solution or blood, followed by calcium silicate-based cements (CSCs) placement: ProRoot mineral trioxide aggregate (MTA) (Dentsply Sirona), Biodentine (Septodont), TotalFill BC (FKG), or pulp capping material (PCM) (Coltene). Color change (Delta E) was assessed using the L* a* b* system at five different timepoints (before and immediately after biomaterial application, 72 h, 7 days, and 6 months). The significance level for statistical analysis was set atp< 0.05. There are statistically significant differences regarding Delta E over time (p< 0.001). Statistical differences are found considering material (p< 0.001), treatment (p= 0.007), or both (p= 0.002). If solely the material or treatment is considered, regardless of time, statistically significant differences are detected (p< 0.001). After a six-month period of evaluation, blood exposure might be a critical factor in biomaterials' color variation. Biodentine presents the lowest discoloration potential, followed by TotalFill and PCM, albeit without statistically significant differences. MTA exhibited the greatest color variation. The selection of biomaterial should consider the material's discoloration potential.