The use of single-cell RNA-Seq to understand virus-host interactions
The use of single-cell RNA-Seq to understand virus-host interactions
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DOI：
10.1016/j.coviro.2018.03.001
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发表时间：
2018-04-01
影响因子：
5.9
通讯作者：
Ciuffi, Angela
中科院分区：
文献类型：
--
作者：
Cristinelli, Sara;Ciuffi, Angela
单细胞分析允许揭示细胞异质性，不仅本身，而且在病毒感染的反应。同样，单细胞转录组分析（scRNA-Seq）可以突出特定的特征，识别具有特定表型的细胞亚群，这与理解病毒宿主相互作用有关。
Single-cell analyses allow uncovering cellular heterogeneity, not only per se, but also in response to viral infection. Similarly, single cell transcriptome analyses (scRNA-Seq) can highlight specific signatures, identifying cell subsets with particular phenotypes, which are relevant in the understanding of virus host interactions.