Study and overview of the novel corona virus disease (COVID-19).
Study and overview of the novel corona virus disease (COVID-19).
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DOI：
10.1016/j.sintl.2020.100037
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发表时间：
2020-01-01
影响因子：
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通讯作者：
Mishra, Animesh
中科院分区：
文献类型：
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作者：
Agarwal, Krishna Mohan;Mohapatra, Swati;Mishra, Animesh
于二零一九年十二月，一种具有肺炎样症状的新型疾病在中国武汉蔓延，该疾病被称为新型冠状病毒病或由SARS CoV-2病毒引起的COVID-19。在几天内，这种疾病成为全球威胁，并于2020年3月11日被世界卫生组织（WHO）称为大流行病，自那时以来，截至2020年7月5日，该疾病已影响全球超过1.5亿人，印度约6.9万人。COVID-19疾病的起源已追溯到蝙蝠，但中间接触尚不清楚。这种疾病通过呼吸道飞沫和受污染的表面传播。在大多数情况下，病毒表现出轻微的症状，如发烧，疲劳，呼吸困难，咳嗽等，如果不采取适当的预防措施，这些症状可能会变得严重。对于患有合并症的人（通常是老年人），这种疾病可能会致命并导致肺炎，急性呼吸道疾病综合征（ARDS）和多器官衰竭，从而影响一个人的呼吸能力，导致呼吸机支持。COVID-19的繁殖数（R ′）远高于其前身以及SARS-CoV和MERS-CoV等基因相似的疾病。本文讨论了SARS-CoV-2病毒的流行病学特征，其与先前引起大流行的病毒（如SARS-CoV-1和MERS-CoV）的系统发育关系，并分析了全球范围内对这一全球大流行的各种反应，重点是印度采取的行动及其结果。
In December 2019, a new disease with pneumonia-like symptoms was spreading throughout Wuhan in China which was entitled as novel coronavirus disease or COVID -19 caused by the virus SARS CoV-2. Within a span of a few days, this disease became a global threat and was termed as a pandemic by the World Health Organization (WHO) on March 11, 2020, since then the disease has affected more than 1.5 crore people worldwide and around 6.9 lakh people in India as of July 5, 2020. The origin of the COVID-19 disease has been traced back to the bats, but the intermediary contact is unknown. The disease spreads by respiratory droplets and contaminated surfaces. In most cases, the virus shows mild symptoms like fever, fatigue, dyspnea, cough, etc. which may become severe if appropriate precautions are not adhered to. For people with comorbidities (usually elderly) the disease may turn deadly and cause pneumonia, Acute Respiratory Disease Syndrome (ARDS), and multi-organ failure, thereby affecting a person's ability to breathe leading to being put on the ventilator support. The reproduction number (Râ„´) of COVID-19 is much higher than its predecessors and genetically similar diseases like SARS-CoV and MERS-CoV. This paper discusses the epidemiological characteristics of the SARS-CoV-2 virus, its phylogenetic relationship with the previous pandemic causing viruses such as SARS-CoV-1 and MERS-CoV and analyzes the various responses to this global pandemic worldwide, focusing on the actions taken by India and their outcomes.