Polyglycerol/Polydopamine-Coated Nanoparticles for Biomedical Applications
Polyglycerol/Polydopamine-Coated Nanoparticles for Biomedical Applications
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DOI：
10.3389/fmats.2022.878455
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发表时间：
2022-04
期刊：
影响因子：
--
通讯作者：
Shingo Sotoma
中科院分区：
文献类型：
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作者：
Shingo Sotoma
纳米颗粒由于其独特的性质在生物医学科学中发挥着积极的作用，这些性质无法从散装材料中获得。因此，了解和控制纳米粒子的物理化学性质对于它们的实际应用越来越重要。表面包覆是控制纳米颗粒物理性质的重要技术，因为包覆层是纳米颗粒与环境接触的第一部分。此外，涂层创造了强大的靶向、治疗、成像和传感机会。本文首先介绍了两种近年来发展起来的优秀涂层，即超支化聚甘油和聚多巴胺，然后重点介绍了聚甘油/聚多巴胺涂层纳米粒子的研究进展。
Nanoparticles play an active role in biomedical science due to their unique properties, which cannot be obtained from bulk materials. Therefore, understanding and controlling the physicochemical properties of nanoparticles are gaining increasing importance for their practical applications. Surface coating is an important technique that controls the physical properties of nanoparticles since the coating is the first part of the nanoparticle that is in contact with the environment. Additionally, the coating creates robust targeting, therapy, imaging, and sensing opportunities. This review first introduced two recently developed outstanding coatings, namely, hyperbranched polyglycerol and polydopamine, and the research achieved by the polyglycerol/polydopamine-coated nanoparticles was then highlighted.