Predicting maximum Roux-en-Y gastric bypass-induced weight reduction preoperative plasma leptin or body weight?
Predicting maximum Roux-en-Y gastric bypass-induced weight reduction preoperative plasma leptin or body weight?
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DOI：
10.1007/s11695-007-9042-1
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发表时间：
2007-02-01
期刊：
影响因子：
2.9
通讯作者：
Strzelczyk, Janusz
中科院分区：
文献类型：
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作者：
Czupryniak, Leszek;Pawlowski, Maciej;Strzelczyk, Janusz
背景：减肥手术后的体重减轻因患者而异，预测其程度往往不准确。本研究的目的是评估术前血浆瘦素和体重在预测Roux-en-Y胃旁路术（RYGBP）后2年内最大体重减轻方面的潜力。（39名女性，29名男性;平均年龄36.4 ± 10.2岁，体重130.3 ± 24.8 kg，BMI 44.4 ± 6.8 kg/m2）接受RYGBP，随访2年。基线和最大随访血浆瘦素和weight进行了assessed.Results：平均最大体重减轻50.5 +/- 19.1公斤（38.0 +/-9.0%，范围24-100公斤），注意到在15 - 4个月后RYGBP。基线血浆瘦素为37.9 ± 04.5 ng/ml，下降至17.4 ± 8.1 ng/ml（P
Background: Weight loss after bariatric surgery varies between patients, and predicting the extent thereof is often inaccurate. The aim of this study was to assess the potential of preoperative plasma leptin and body weight in predicting the maximum weight loss within 2 years after Roux-en-Y gastric bypass (RYGBP).Methods: The study comprised 68 subjects (39 women, 29 men; mean age 36.4 +/- 10.2 years, body weight 130.3 +/- 24.8 kg, BMI 44.4 +/- 6.8 kg/m(2)) undergoing RYGBP who were followed for 2 years. Baseline and maximum follow-up plasma leptin and weight were assessed.Results: Mean maximum weight reduction of 50.5 +/- 19.1 kg (38.0 +/- 9.0%, range 24-100 kg) was noted at 15 4 months after RYGBP. Baseline plasma leptin was 37.9 +/-:04.5 ng/ml, and decreased to 17.4 +/- 8.1 ng/ml (P