Fabrication of poly(dimethylsiloxane) microfluidic system based on masters directly printed with an office laser printer
Fabrication of poly(dimethylsiloxane) microfluidic system based on masters directly printed with an office laser printer
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DOI：
10.1016/j.chroma.2005.07.001
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发表时间：
2005-09-30
影响因子：
4.1
通讯作者：
Chen, HY
中科院分区：
文献类型：
--
作者：
Bao, N;Zhang, Q;Chen, HY
基于聚（二甲基硅氧烷）（PDMS）的微流控系统的应用如今更加流行。以前的PDMS微通道母版的制造方法需要复杂的步骤和/或特殊的设备。在本文中，我们演示了用办公激光打印机（1200 dpi）在透明胶片上打印的碳粉可以用作母版的正浮雕。透明薄膜分两步印刷，以获得相同的交叉线印刷质量。使用激光打印母版，制造的 PDMS 微通道的深度约为 100 毫米。 10μm，最小宽度约。 60亩。 PDMS/PDMS 微通道的表面特征通过 SEM 进行。通过测量电渗流（EOF）和欧姆曲线来研究它们的电动特性。使用PDMS/PDMS微芯片毛细管电泳系统，电活性生物分子和非电活性无机离子分别得到很好的分离。这种简单的方法可以使在更普通的实验室中无需特殊设备即可轻松进行 PDMS 微流体系统的研究。 (c) 2005 Elsevier B.V. 保留所有权利。
Applications of poly(dimethylsiloxane) (PDMS)-based microfluidic systems are more popular nowadays. Previous fabrication methods of the masters for PDMS microchannels require complicated steps and/or special device. In this paper, we demonstrated that the toner printed on the transparency film with the office laser printer (1200 dpi) can be used as the positive relief of the masters. The transparency film was printed in two steps in order to obtain the same printing quality for the crossed lines. With the laser-printed master, the depth of the fabricated PDMS microchannels was ca. 10 mu m and the smallest width was ca. 60 mu m. Surface characteristics of the PDMS/PDMS microchannels were performed with SEM. Their electrokinetic properties were investigated by the aids of the measurement of electroosmotic flow (EOF) and the Ohm's curve. Using the PDMS/PDMS microchip CE systems, electroactive biological molecules and non-electroactive inorganic ions were well separated, respectively. This simple approach could make it easy to carry out the studies of PDMS microfluidic systems in more general labs without special devices. (c) 2005 Elsevier B.V. All rights reserved.