Fortifying the link between SIRT1, resveratrol, and mitochondrial function.
Fortifying the link between SIRT1, resveratrol, and mitochondrial function.
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DOI:
10.1016/j.cmet.2012.04.016
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发表时间:
2012-05-02
期刊:
影响因子:
29
通讯作者:
Denu JM
中科院分区:
文献类型:
--
作者:
Denu JM
The molecular mechanisms behind the health benefits of resveratrol remain enigmatic and controversial. Here, Price et al. establish a clear chemical-genetic connection between SIRT1 and resveratrol, providing strong evidence that SIRT1 is critical for resveratrol to stimulate mitochondrial biogenesis and a switch toward oxidative muscle fibers.
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影响因子:
29
作者:
Pearson KJ;Baur JA;Lewis KN;Peshkin L;Price NL;Labinskyy N;Swindell WR;Kamara D;Minor RK;Perez E;Jamieson HA;Zhang Y;Dunn SR;Sharma K;Pleshko N;Woollett LA;Csiszar A;Ikeno Y;Le Couteur D;Elliott PJ;Becker KG;Navas P;Ingram DK;Wolf NS;Ungvari Z;Sinclair DA;de Cabo R
通讯作者:
de Cabo R
影响因子:
3.7
作者:
Barger JL;Kayo T;Vann JM;Arias EB;Wang J;Hacker TA;Wang Y;Raederstorff D;Morrow JD;Leeuwenburgh C;Allison DB;Saupe KW;Cartee GD;Weindruch R;Prolla TA
通讯作者:
Prolla TA
影响因子:
4.8
作者:
Kaeberlein, M;McDonagh, T;Kennedy, BK
通讯作者:
Kennedy, BK
影响因子:
29
作者:
Price NL;Gomes AP;Ling AJ;Duarte FV;Martin-Montalvo A;North BJ;Agarwal B;Ye L;Ramadori G;Teodoro JS;Hubbard BP;Varela AT;Davis JG;Varamini B;Hafner A;Moaddel R;Rolo AP;Coppari R;Palmeira CM;de Cabo R;Baur JA;Sinclair DA
通讯作者:
Sinclair DA
影响因子:
64.8
作者:
Howitz, KT;Bitterman, KJ;Sinclair, DA
通讯作者:
Sinclair, DA