Axonal regeneration on mature human brain tissue sections in culture.
Axonal regeneration on mature human brain tissue sections in culture.
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培养中成熟人脑组织切片的轴突再生。
DOI:
10.1002/ana.410260414
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发表时间:
1989
影响因子:
11.2
通讯作者:
Privitera,M
中科院分区:
文献类型:
--
作者:
Crutcher,KA;Privitera,M
Fresh frozen sections of the temporal lobe from patients undergoing surgical resection for the control of epilepsy were used as a substrate in tissue culture to test for neurite growth‐promoting activity. Robust neurite growth from ganglia of embryonic chicks was observed on gray matter regions of the sections and little growth was observed on white matter regions. These results indicate that the dichotomy between gray and white matter regions of the mature central nervous system in supporting neurite growth is present in human brain tissue and supports the general hypothesis that white matter in the mature central nervous system inhibits neurite regeneration but that gray matter will support neurite growth.