Effects of Age, Time Period, and Birth Cohort on the Prevalence of Diabetes and Obesity in Korean Men
Effects of Age, Time Period, and Birth Cohort on the Prevalence of Diabetes and Obesity in Korean Men
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DOI：
10.2337/dc07-0531
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发表时间：
2008-02-01
期刊：
影响因子：
16.2
通讯作者：
Cho, Sung-Il
中科院分区：
文献类型：
--
作者：
Kwon, Jin-Won;Song, Yun-Mi;Cho, Sung-Il
目的-我们研究了1992年至2000年8年间，1933年至1972年出生队列中412,881名韩国男性糖尿病、肥胖和超重患病率的变化，并分别分析了年龄、时间段、研究设计和方法-这项研究包括1992年韩国政府机构和学校的20至59岁的男性雇员。根据1992年的自我报告或空腹血糖水平（>= 126 mg/ml，7.0 mmol/l）诊断糖尿病。年龄-时期-队列模型用于估计年龄、时期和出生队列的影响。结果-在1933年至1972年的韩国男性出生队列中，28-59岁男性的糖尿病、肥胖和超重的年龄特异性患病率每年增加0.41% 1992 ~ 2000年，分别为3.03 ~ 6.29%、0.18%（0.70 ~ 2.16%）和1.49%（23.48 ~ 35.41%）。糖尿病的相对变化在年轻人群中最大（8年内增加>400%），并与肥胖的变化相对应。除了年龄的贡献，明确的队列和期间的影响是明显的糖尿病，虽然幅度的影响是略低于肥胖症。结论-预防糖尿病通过控制肥胖，特别是在年轻男子，显然需要强调。
OBJECTIVE - we examined changes in the prevalence of diabetes, obesity, and overweight in 412,881 Korean men in birth cohorts from 1933 to 1972 over 8 years from 1992 to 2000 and separately analyzed the effects of age, time period, and birth cohort.RESEARCH DESIGN AND METHODS - The study included male employees of Korean government organizations and schools who were between 20 and 59 years of age in 1992. Diabetes was diagnosed on the basis of self-reports in 1992 or fasting blood glucose levels ( >= 126 mg/ml, 7.0 mmol/l). The age-period-cohort model was used to estimate the effects of age, time period, and birth cohort.RESULTS - in Korean male birth cohorts from 1933 to 1972, the age-specific prevalence of diabetes, obesity, and overweight in men aged 28-59 years increased annually by 0.41% (3.03 to 6.29%), 0.18% (0.70 to 2.16%), and 1.49% (23.48 to 35.4.1%, respectively, from 1992 to 2000. The relative change in diabetes was largest among the younger cohorts (>400% increase over 8 years) and corresponded to the change in obesity. Apart from the contribution of age, clear cohort and period effects were evident for diabetes, although the magnitude Of the effect was slightly less than that for obesity.CONCLUSIONS - Prevention of diabetes through the control of obesity, particularly in young men, clearly needs to be emphasized.