Graphene oxide-photosensitizer conjugate as a redox-responsive theranostic agent
Graphene oxide-photosensitizer conjugate as a redox-responsive theranostic agent
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DOI：
10.1039/c2cc35197h
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发表时间：
2012-01-01
影响因子：
4.9
通讯作者：
Choi, Yongdoo
中科院分区：
文献类型：
--
作者：
Cho, Youngnam;Choi, Yongdoo
纳米级氧化石墨烯-光敏剂与氧化还原反应可切割二硫化物连接剂偶联是无荧光和无光毒性的，即使在光照射下。它在癌细胞内变得高度荧光和光毒性，谷胱甘肽被用作激活光敏剂的引发剂。
A nano-sized graphene oxide-photosensitizer conjugate with a redox-responsive cleavable disulfide linker is non-fluorescent and non-phototoxic, even upon light irradiation. It becomes highly fluorescent and phototoxic inside cancer cells, where glutathione is used as an initiator for activating the photosensitizer.