The economic burden of systemic lupus erythematosus
The economic burden of systemic lupus erythematosus
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DOI：
10.1016/j.berh.2012.08.006
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发表时间：
2012-10-01
影响因子：
5.2
通讯作者：
Yelin, Edward
中科院分区：
文献类型：
--
作者：
Panopalis, Pantelis;Clarke, Ann E.;Yelin, Edward
系统性红斑狼疮(SLE)是一种以多变和不可预测的表现为特征的系统性自身免疫性疾病，可严重影响一个人的身心健康、社会生活以及获得和维持有报酬的工作的能力。疾病本身或治疗的结果可能会对重要器官造成损害，病人往往会消耗大量的保健资源，并产生可观的保健费用。此外，系统性红斑狼疮往往影响青壮年和中年妇女，而此时她们通常最积极地参与劳动大军，并可能对获得和维持就业以及在事业上取得进步产生重要影响。一些研究试图评估与系统性红斑狼疮相关的保健成本(直接成本)、系统性红斑狼疮对就业的影响以及由于工作生产率下降而产生的相关成本(间接成本)。在这篇文章中，我们回顾了最近的一些研究，这些研究增加了我们目前对系统性红斑狼疮经济负担的理解。(C)2012爱思唯尔有限公司。保留所有权利。
Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterised by variable and unpredictable manifestations that can severely affect a person's physical and mental well-being, social life and ability to acquire and maintain gainful employment. Damage to vital organs may ensue as a result of the disease itself or as a consequence of treatment, and patients often consume substantial health-care resources and incur considerable health-care costs. Furthermore, SLE tends to affect women in young and middle adulthood, at a time in their lives when they are usually most actively engaged in the workforce, and can have important consequences with respect to acquiring and maintaining employment and advancing in one's career. A number of studies have attempted to assess the health-care costs (direct costs) associated with SLE, the effects of SLE on employment and the associated costs due to decreases in work productivity (indirect costs). In this article, we review a number of recent studies that have added to our current understanding of the economic burden of SLE. (C) 2012 Elsevier Ltd. All rights reserved.