Paroxysmal Nocturnal Hemoglobinuria: Termination in Acute Monocytic Leukemia and Reappearance after Chemotherapy with N4-Palmitoyl-l-β9-D-Arabinofuranosylcytosine (PL-AC) and Vincristine
Paroxysmal Nocturnal Hemoglobinuria: Termination in Acute Monocytic Leukemia and Reappearance after Chemotherapy with N4-Palmitoyl-l-β9-D-Arabinofuranosylcytosine (PL-AC) and Vincristine
复制标题
阵发性睡眠性血红蛋白尿：急性单核细胞白血病的终止和 N4-棕榈酰-l-β9-D-阿拉伯呋喃糖基胞嘧啶 (PL-AC) 和长春新碱化疗后的复发
DOI：
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发表时间：
1987
期刊：
影响因子：
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通讯作者：
K. Takatsuki
中科院分区：
文献类型：
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作者：
F. Kawano;M. Chosa;M. Matsuoka;N. Oyamada;K. Takatsuki
Acute monocytic leukemia developed in a 77-year-old woman about 18 months after a diagnosis of paroxysmal nocturnal hemoglobinuria (PNH) had been made. The classical features of PNH disappeared with the onset of the leukemia. Chemotherapy with N4-palmitoyl-1-beta-D-arabinosylcytosine and vincristine resulted in the disappearance of leukemic cells in the bone marrow, during which time intravascular hemolysis recurred and the results of a Ham's test were again positive. The anemia and thrombocytopenia, however, were not improved. The present case report suggests the disappearance of the leukemic cells to imply not bone marrow remission but the return of PNH.
